The role of bacteria in the pathogenesis of ulcerative colitis

M Sasaki, JMA Klapproth - Journal of signal transduction, 2012 - Wiley Online Library
Factors implicated in the pathophysiology of ulcerative colitis (UC) are an abnormal immune
response, defect in intestinal epithelial barrier function, and gut microbiota. Currently, it is …

Cross talk between the gut microbiome and host immune response in ulcerative colitis: Nonpharmacological strategies to improve homeostasis

BM Bullard, BN VanderVeen… - American Journal …, 2022 - journals.physiology.org
Ulcerative colitis (UC) is a chronic disease that is characterized by diffuse inflammation of
the colonic and rectal mucosa. The burden of UC is rising globally with significant disparities …

Influence of microbiota on intestinal immune system in ulcerative colitis and its intervention

SL Zhang, SN Wang, CY Miao - Frontiers in immunology, 2017 - frontiersin.org
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) with chronic and recurrent
characteristics caused by multiple reasons. Although the pathogenic factors have not been …

Cross talk between gut microbiota and intestinal mucosal immunity in the development of ulcerative colitis

J Zou, C Liu, S Jiang, D Qian, J Duan - Infection and Immunity, 2021 - Am Soc Microbiol
Ulcerative colitis (UC), a nonspecific inflammatory disease, is characterized by inflammation
and mucosal damage in the colon, and its prevalence in the world is increasing …

Interplay between cellular and molecular mechanisms underlying inflammatory bowel diseases development—a focus on ulcerative colitis

I Samoilă, S Dinescu, M Costache - Cells, 2020 - mdpi.com
Inflammatory bowel diseases (IBD) are defined by the continuous inflammation of the
gastrointestinal tract. During inflammation, the number of pathogens in the intestinal …

Impact of gut Microbiome alteration in Ulcerative Colitis patients on disease severity and outcome

OM Basha, RA Hafez, SM Salem, RH Anis… - Clinical and …, 2023 - Springer
Background Ulcerative colitis is a heterogeneous disease in terms of disease course,
location, and therapeutic response. The current study was done to assess the alteration of …

Immune response and inflammatory pathway of ulcerative colitis

N Tatiya-Aphiradee, W Chatuphonprasert… - Journal of basic and …, 2018 - degruyter.com
Ulcerative colitis (UC) is an idiopathic relapsing inflammatory disease. Although the etiology
of UC remains unclear, it could be characterized by inflammation of the intestinal mucosa …

[PDF][PDF] Intestinal bacteria and ulcerative colitis

JH Cummings, GT Macfarlane… - Current issues in intestinal …, 2003 - caister.com
Convincing evidence from both animal models and the study of patients with ulcerative
colitis (UC) implicates the intestinal microflora in the initiation and maintenance of the …

The Role of the Microbiome in the Pathogenesis and Treatment of Ulcerative Colitis—A Literature Review

G Świrkosz, A Szczygieł, K Logoń, M Wrześniewska… - Biomedicines, 2023 - mdpi.com
Ulcerative colitis (UC) is a chronic inflammatory bowel disease affecting the colon and
rectum. UC's pathogenesis involves colonic epithelial cell abnormalities and mucosal barrier …

Transcriptional signatures that define ulcerative colitis in remission

CG Fenton, H Taman, J Florholmen… - Inflammatory bowel …, 2021 - academic.oup.com
Background This study addresses whether existing specific transcriptional profiles can
improve and support the current status of the definition of ulcerative colitis (UC) remission …