Hospitalizations and mortality in patients with secondary mitral regurgitation and heart failure: the COAPT trial

G Giustino, A Camaj, SR Kapadia, S Kar… - Journal of the American …, 2022 - jacc.org
Background The impact of transcatheter edge-to-edge repair (TEER) on the rate and
prognostic impact of hospitalizations in patients with heart failure (HF) and severe secondary …

Derivation and validation of a clinical risk score for COAPT-ineligible patients who underwent transcatheter edge-to-edge repair

A Scotti, A Latib, AP Rubbio, L Testa, M Adamo… - The American Journal of …, 2023 - Elsevier
Up to half of real-world patients with secondary mitral regurgitation who underwent
transcatheter edge-to-edge repair (TEER) do not meet the highly selective COAPT …

Age-related outcomes after transcatheter mitral valve repair in patients with heart failure: analysis from COAPT

C Song, MV Madhavan, JA Lindenfeld… - Cardiovascular …, 2022 - jacc.org
Objectives The aim of this study was to assess the impact of age on outcomes in patients
undergoing transcatheter edge-to-edge repair (TEER) from the COAPT (Cardiovascular …

Predictors of clinical response to transcatheter reduction of secondary mitral regurgitation: the COAPT trial

PA Grayburn, A Sannino, DJ Cohen, S Kar… - Journal of the American …, 2020 - jacc.org
Background Transcatheter mitral valve repair with the MitraClip results in marked clinical
improvement in some but not all patients with secondary mitral regurgitation (MR) and heart …

Outcomes stratified by adapted inclusion criteria after mitral edge-to-edge repair

B Koell, M Orban, J Weimann, M Kassar… - Journal of the American …, 2021 - jacc.org
Background Although mitral valve transcatheter edge-to-edge repair (M-TEER) achieves
symptomatic benefit for a broad spectrum of patients with relevant secondary mitral …

Relationship between residual mitral regurgitation and clinical and quality-of-life outcomes after transcatheter and medical treatments in heart failure: COAPT trial

S Kar, MJ Mack, JA Lindenfeld, WT Abraham… - Circulation, 2021 - Am Heart Assoc
Background: In the randomized COAPT trial (Cardiovascular Outcomes Assessment of the
MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral …

Two randomized clinical trials on the treatment of secondary mitral regurgitation—contradictory or complementary?

GHL Tang, S Verma, DL Bhatt - JAMA cardiology, 2019 - jamanetwork.com
Treatment of symptomatic primary (or degenerative) mitral regurgitation (MR) is well defined,
with surgical repair being the gold standard and transcatheter repair indicated in patients …

Cost-effectiveness of transcatheter mitral valve repair versus medical therapy in patients with heart failure and secondary mitral regurgitation: results from the COAPT …

SJ Baron, K Wang, SV Arnold, EA Magnuson… - Circulation, 2019 - Am Heart Assoc
Background: The COAPT trial (Cardiovascular Outcomes Assessment of the MitraClip
Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation) …

Health status changes and outcomes in patients with heart failure and mitral regurgitation: COAPT trial

SV Arnold, GW Stone, MJ Mack, AK Chhatriwalla… - Journal of the American …, 2020 - jacc.org
Abstract Background In the COAPT (Cardiovascular Outcomes Assessment of the MitraClip
Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation) trial …

3-year outcomes of transcatheter mitral valve repair in patients with heart failure

MJ Mack, JA Lindenfeld, WT Abraham, S Kar… - Journal of the American …, 2021 - jacc.org
Abstract Background In the COAPT (Cardiovascular Outcomes Assessment of the MitraClip
Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation) trial …