High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods
RGS9 is a member of the RGS family of GTPase accelerating proteins (GAPs) for
heterotrimeric G proteins. We have explored its contribution to GTPase acceleration in …
heterotrimeric G proteins. We have explored its contribution to GTPase acceleration in …
Modules in the photoreceptor RGS9-1· Gβ5L GTPase-accelerating protein complex control effector coupling, GTPase acceleration, protein folding, and stability
W He, L Lu, X Zhang, HM El-Hodiri, CK Chen… - Journal of Biological …, 2000 - ASBMB
RGS (regulators of Gprotein signaling) proteins regulate G protein signaling by accelerating
GTP hydrolysis, but little is known about regulation of GTPase-accelerating protein (GAP) …
GTP hydrolysis, but little is known about regulation of GTPase-accelerating protein (GAP) …
Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP
G Hu, Z Zhang, TG Wensel - Journal of Biological Chemistry, 2003 - ASBMB
The GTPase-accelerating protein (GAP) complex RGS9-1· Gβ 5 plays an important role in
the kinetics of light responses by accelerating the GTP hydrolysis of Gα t in vertebrate …
the kinetics of light responses by accelerating the GTP hydrolysis of Gα t in vertebrate …
R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1
G Hu, TG Wensel - Proceedings of the National Academy of …, 2002 - National Acad Sciences
The regulator of G protein signaling (RGS)-9-1⋅ Gβ5 complex forms the GTPase
accelerating protein for Gαt in vertebrate photoreceptors. Although the complex is soluble …
accelerating protein for Gαt in vertebrate photoreceptors. Although the complex is soluble …
RGS9-Gβ5 substrate selectivity in photoreceptors: opposing effects of constituent domains yield high affinity of RGS interaction with the G protein-effector complex
NP Skiba, KA Martemyanov, A Elfenbein… - Journal of Biological …, 2001 - ASBMB
RGS proteins regulate the duration of G protein signaling by increasing the rate of GTP
hydrolysis on G protein α subunits. The complex of RGS9 with type 5 G protein β subunit …
hydrolysis on G protein α subunits. The complex of RGS9 with type 5 G protein β subunit …
Prolonged photoresponses and defective adaptation in rods of Gβ5-/-mice
CM Krispel, CK Chen, MI Simon… - Journal of …, 2003 - Soc Neuroscience
Timely deactivation of G-protein signaling is essential for the proper function of many cells,
particularly neurons. Termination of the light response of retinal rods requires GTP …
particularly neurons. Termination of the light response of retinal rods requires GTP …
Phosphorylation of RGS9-1 by an endogenous protein kinase in rod outer segments
Inactivation of the visual G protein transducin, during recovery from photoexcitation, is
regulated by RGS9-1, a GTPase-accelerating protein of the ubiquitous RGS protein family …
regulated by RGS9-1, a GTPase-accelerating protein of the ubiquitous RGS protein family …
The effector enzyme regulates the duration of G protein signaling in vertebrate photoreceptors by increasing the affinity between transducin and RGS protein
NP Skiba, JA Hopp, VY Arshavsky - Journal of Biological Chemistry, 2000 - ASBMB
The photoreceptor-specific G protein transducin acts as a molecular switch, stimulating the
activity of its downstream effector in its GTP-bound form and inactivating the effector upon …
activity of its downstream effector in its GTP-bound form and inactivating the effector upon …