Advances in Nod-like receptors (NLR) biology
The innate immune system is composed of a wide repertoire of conserved pattern
recognition receptors (PRRs) able to trigger inflammation and host defense mechanisms in …
recognition receptors (PRRs) able to trigger inflammation and host defense mechanisms in …
NOD‐like receptor (NLR) signaling beyond the inflammasome
PJ Shaw, M Lamkanfi… - European journal of …, 2010 - Wiley Online Library
Recent years have witnessed a marked progress in our knowledge of NOD‐like receptors
(NLR), intracellular sensors with central roles in innate and adaptive immunity. A majority of …
(NLR), intracellular sensors with central roles in innate and adaptive immunity. A majority of …
NOD-like receptors and the innate immune system: coping with danger, damage and death
K Kersse, MJM Bertrand, M Lamkanfi… - Cytokine & growth factor …, 2011 - Elsevier
Members of the family of NOD-like receptors (NLRs) play essential roles in innate immunity
by detecting intracellular 'pathogen-associated molecular patterns'(PAMPs) and 'danger …
by detecting intracellular 'pathogen-associated molecular patterns'(PAMPs) and 'danger …
Function of Nod‐like receptors in microbial recognition and host defense
L Franchi, N Warner, K Viani… - Immunological reviews, 2009 - Wiley Online Library
Nucleotide oligomerization domain (NOD)‐like receptors (NLRs) are a specialized group of
intracellular proteins that play a critical role in the regulation of the host innate immune …
intracellular proteins that play a critical role in the regulation of the host innate immune …
[HTML][HTML] Activation and regulation mechanisms of NOD-like receptors based on structural biology
U Ohto - Frontiers in immunology, 2022 - frontiersin.org
Innate immunity is a primary defense system against microbial infections. Innate immune
pattern recognition receptors (PRRs) play pivotal roles in detection of invading pathogens …
pattern recognition receptors (PRRs) play pivotal roles in detection of invading pathogens …
[HTML][HTML] The NLR family of innate immune and cell death sensors
B Sundaram, RE Tweedell, SP Kumar, TD Kanneganti - Immunity, 2024 - cell.com
Nucleotide-binding oligomerization domain (NOD)-like receptors, also known as nucleotide-
binding leucine-rich repeat receptors (NLRs), are a family of cytosolic pattern recognition …
binding leucine-rich repeat receptors (NLRs), are a family of cytosolic pattern recognition …
[HTML][HTML] Mechanisms of NOD-like receptor-associated inflammasome activation
H Wen, EA Miao, JPY Ting - Immunity, 2013 - cell.com
A major function of a subfamily of NLR (nucleotide-binding domain, leucine-rich repeat
containing, or NOD-like receptor) proteins is in inflammasome activation, which has been …
containing, or NOD-like receptor) proteins is in inflammasome activation, which has been …
[HTML][HTML] Intracellular NOD-like receptors in host defense and disease
The innate immune system comprises several classes of pattern recognition receptors,
including Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-1-like receptors …
including Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-1-like receptors …
[HTML][HTML] NOD-like receptors: master regulators of inflammation and cancer
M Saxena, G Yeretssian - Frontiers in immunology, 2014 - frontiersin.org
Cytosolic NOD-like receptors (NLRs) have been associated with human diseases including
infections, cancer, and autoimmune and inflammatory disorders. These innate immune …
infections, cancer, and autoimmune and inflammatory disorders. These innate immune …
[HTML][HTML] Functions of NOD-like receptors in human diseases
Y Zhong, A Kinio, M Saleh - Frontiers in immunology, 2013 - frontiersin.org
Nucleotide-binding and oligomerization domain NOD-like receptors (NLRs) are highly
conserved cytosolic pattern recognition receptors that perform critical functions in surveying …
conserved cytosolic pattern recognition receptors that perform critical functions in surveying …