[HTML][HTML] Mitochondrial transfer from bone marrow mesenchymal stem cells to motor neurons in spinal cord injury rats via gap junction

H Li, C Wang, T He, T Zhao, Y Chen, Y Shen… - Theranostics, 2019 - ncbi.nlm.nih.gov
Recent studies have demonstrated that bone marrow mesenchymal stem cells (BMSCs)
protect the injured neurons of spinal cord injury (SCI) from apoptosis while the underlying …

Mitochondrial transplantation attenuates neural damage and improves locomotor function after traumatic spinal cord injury in rats

MW Lin, SY Fang, JYC Hsu, CY Huang… - Frontiers in …, 2022 - frontiersin.org
Mitochondrial dysfunction is a hallmark of secondary neuroinflammatory responses and
neuronal death in spinal cord injury (SCI). Even though mitochondria-based therapy is an …

Transfer of mitochondria from mesenchymal stem cells derived from induced pluripotent stem cells attenuates hypoxia-ischemia-induced mitochondrial dysfunction in …

Y Yang, G Ye, YL Zhang, HW He, BQ Yu… - Neural regeneration …, 2020 - journals.lww.com
Mitochondrial dysfunction in neurons has been implicated in hypoxia-ischemia-induced
brain injury. Although mesenchymal stem cell therapy has emerged as a novel treatment for …

Mesenchymal stromal cell mitochondrial transfer as a cell rescue strategy in regenerative medicine: a review of evidence in preclinical models

YL Tan, SP Eng, P Hafez, N Abdul Karim… - Stem Cells …, 2022 - academic.oup.com
Mesenchymal stromal cells (MSC) have excellent clinical potential and numerous properties
that ease its clinical translation. Mitochondria play a crucial role in energy metabolism …

Regenerative abilities of mesenchymal stem cells through mitochondrial transfer

S Paliwal, R Chaudhuri, A Agrawal… - Journal of biomedical …, 2018 - Springer
The past decade has witnessed an upsurge in studies demonstrating mitochondrial transfer
as one of the emerging mechanisms through which mesenchymal stem cells (MSCs) can …

Mitochondrial transfer from mesenchymal stem cells to neural stem cells protects against the neurotoxic effects of cisplatin

N Boukelmoune, GS Chiu, A Kavelaars… - Acta neuropathologica …, 2018 - Springer
Mesenchymal stem cells (MSCs) transfer healthy mitochondria to damaged acceptor cells
via actin-based intercellular structures. In this study, we tested the hypothesis that MSCs …

Mitochondrial transfer from mesenchymal stem cells improves neuronal metabolism after oxidant injury in vitro: The role of Miro1

N Tseng, SC Lambie, CQ Huynh… - Journal of Cerebral …, 2021 - journals.sagepub.com
Stroke-induced cerebral ischemia is a major cause of death and disability. The disruption of
blood flow results in neuronal and glial cell death leading to brain injury. Reperfusion …

Mechanisms behind therapeutic potentials of mesenchymal stem cell mitochondria transfer/delivery

K Malekpour, A Hazrati, S Soudi… - Journal of Controlled …, 2023 - Elsevier
Mesenchymal stromal/stem cells (MSCs) perform their therapeutic effects through various
mechanisms, including their ability to differentiate, producing different growth factors …

Mesenchymal stem cells-derived mitochondria transplantation mitigates I/R-induced injury, abolishes I/R-induced apoptosis, and restores motor function in acute …

Z Pourmohammadi-Bejarpasi, AM Roushandeh… - Brain Research …, 2020 - Elsevier
Acute ischemia stroke (AIS) is one of the leading causes of mortality and disability
worldwide, and its neurological impacts are devastating and permanent. There is no efficient …

Mitochondria transfer enhances proliferation, migration, and osteogenic differentiation of bone marrow mesenchymal stem cell and promotes bone defect healing

Y Guo, X Chi, Y Wang, BC Heng, Y Wei… - Stem cell research & …, 2020 - Springer
Background Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is
considered a promising therapeutic approach for bone defect repair. However, during the …