Expansion of the classification of FTLD-TDP: distinct pathology associated with rapidly progressive frontotemporal degeneration
Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) can typically be
categorized into one of four distinct histopathologic patterns of TDP-43 pathology, types A to …
categorized into one of four distinct histopathologic patterns of TDP-43 pathology, types A to …
Reappraisal of TDP-43 pathology in FTLD-U subtypes
IR Mackenzie, M Neumann - Acta neuropathologica, 2017 - Springer
Frontotemporal lobar degeneration with tau-negative, ubiquitin-immunoreactive (-ir)
pathology (FTLD-U) is subclassified based on the type and cortical laminar distribution of …
pathology (FTLD-U) is subclassified based on the type and cortical laminar distribution of …
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions
TAR DNA-binding protein 43 (TDP-43) is a major pathological protein of sporadic and
familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions …
familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions …
Severe subcortical TDP-43 pathology in sporadic frontotemporal lobar degeneration with motor neuron disease
NJ Brandmeir, F Geser, LK Kwong, E Zimmerman… - Acta …, 2008 - Springer
Abstract Recently, TDP-43, a 43 kDa nuclear TAR DNA-binding protein, was identified as
the major disease protein in frontotemporal lobar degeneration with ubiquitinated inclusions …
the major disease protein in frontotemporal lobar degeneration with ubiquitinated inclusions …
Pathological, imaging and genetic characteristics support the existence of distinct TDP-43 types in non-FTLD brains
KA Josephs, ME Murray, N Tosakulwong… - Acta …, 2019 - Springer
TDP-43 is present in a high proportion of aged brains that do not meet criteria for
frontotemporal lobar degeneration (FTLD). We determined whether there are distinct TDP …
frontotemporal lobar degeneration (FTLD). We determined whether there are distinct TDP …
Frontotemporal lobar degeneration TDP-43-immunoreactive pathological subtypes: clinical and mechanistic significance
Frontotemporal lobar degeneration with TPD-43-immunoreactive pathology (FTLD-TDP) is
subclassified based on the type and cortical laminar distribution of neuronal inclusions. The …
subclassified based on the type and cortical laminar distribution of neuronal inclusions. The …
Evaluation of subcortical pathology and clinical correlations in FTLD-U subtypes
KA Josephs, A Stroh, B Dugger, DW Dickson - Acta neuropathologica, 2009 - Springer
Frontotemporal lobar degeneration (FTLD) can be classified as tau-positive (FTLD-tau) and
tau-negative FTLD. The most common form of tau-negative FTLD is associated with …
tau-negative FTLD. The most common form of tau-negative FTLD is associated with …
TDP-43 subtypes are associated with distinct atrophy patterns in frontotemporal dementia
Background: We sought to describe the antemortem clinical and neuroimaging features
among patients with frontotemporal lobar degeneration with TDP-43 immunoreactive …
among patients with frontotemporal lobar degeneration with TDP-43 immunoreactive …
TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD
S Roeber, IRA Mackenzie, HA Kretzschmar… - Acta …, 2008 - Springer
Frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) is the most
common neuropathological subtype of frontotemporal dementias. While TDP-43 is the …
common neuropathological subtype of frontotemporal dementias. While TDP-43 is the …
Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration
Abstract TAR-DNA binding protein-43 (TDP-43) proteinopathy is seen in multiple brain
diseases. A standardized terminology was recommended recently for common age-related …
diseases. A standardized terminology was recommended recently for common age-related …