E. Donnall Thomas, MD, stands as a luminary in the realms of bone marrow transplantation
(BMT) and immunotherapy. Renowned for pioneering BMT and establishing the bedrock of …

Cellular immunotherapy harnesses the body's own immune system to fight cancer by using
engineered T cells, macrophages, or natural killer (NK) cells. Compared to chimeric antigen …

Background & Aim The cell therapy field has grown exponentially as a prominent
therapeutic for several diseases, including cancer. With growing interest in off-the-shelf …

Immune cell therapy has become a cornerstone in cancer therapy. However, the needs for
new therapies targeting acute myeloid leukemia (AML) and solid tumors remains high …

Natural killer (NK) cells recognize targets stressed by malignant transformation or infection
(particularly CMV). We now know that NK cells can be long-lived and remember past …

The potential of natural killer (NK) cells to target numerous malignancies in vitro has been
well documented; however, only limited success has been seen in the clinic. Although NK …

Recently, there has been a substantial gain in our understanding of the role that natural
killer (NK) cells play in mediating innate host immune responses against viruses and cancer …

Despite many advances, the treatment of acute myeloid leukemia (AML) remains
challenging, and few patients are cured by therapies other than allogeneic hematopoietic …

Background The use of bispecific Innate Cell Engagers (ICE®) has become a successful
strategy for immune cell activation and killing of tumor cells through antibody-dependent …

New cancer-fighting cells enter trials | Science news careers commentary Journals Science
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