FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-
amino-3-phenylpropanoyl] amino]-3-phenylpropanoyl] amino]-4-methylpentanoyl] amino] …

Natural killer (NK) cells are members of the innate immune system that recognize target cells
via activating and inhibitory signals received through cell receptors. Derived from the …

Chimeric antigen receptors (CARs) significantly enhance the anti-tumor activity of immune
effector cells. Although most studies have evaluated CAR expression in T cells, here we …

Adoptive immunotherapy using immune effector cells has revolutionized cancer treatments
with approval of two autologous chimeric antigen receptor (CAR) T cell therapies by the US …

RESULTS Figure 7. FT516 effectively mediates ADCC in an in vivo ovarian cancer model.
NSG mice were inoculated IP with 1E5 SKOV-3 cells expressing the firefly luciferase gene …

Natural killer (NK) cells play a crucial role in host immunity by detecting cells that
downregulate MHC class I presentation and upregulate stress ligands, as commonly seen in …

Natural killer (NK) cells are advantaged immune cells and play a pivotal role in both innate
and adaptive immune responses. To date, autogenous and allogenic NK cells have been …

The development of methods to derive induced pluripotent stem cells (iPSCs) has propelled
stem cell research, and has the potential to revolutionize many areas of medicine, including …

Recent advances in cellular therapies for patients with cancer, including checkpoint
blockade and ex vivo-expanded, tumor-specific T cells, have demonstrated that targeting the …

Primary human natural killer (NK) cells recognize and subsequently eliminate virus infected
cells, tumor cells, or other aberrant cells. However, cancer cells are able to develop tumor …