Natural killer (NK) cells are lymphocytes of the innate immune system. A key feature of NK
cells is their ability to recognize a wide range of cells in distress, particularly tumour cells …

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

To circumvent this issue, the authors triple-modified iPSC-derived NK cells to express a
CD19 targeting CAR for antigen specificity, a high affinity, noncleavable CD16 (hnCD16) to …

Imai et al.; Genetic modification of primary natural killer cells overcomes inhibitory signals
and induces specific killing of leuke mic cells; Blood, vol. 106, No. 1, pp. 376-383, Jul. 1 …

Current cell and gene therapy medicines for oncology have reshaped how cancer is treated.
Specifically, chimeric antigen receptor (CAR)-T cells have demonstrated that cell therapy …

Background Natural killer (NK) cells are innate immune cells that play a key role in in tumor
immune surveillance. Recent advances allow for the derivation of immune cells, including …

Chimeric antigen receptor (CAR) T cells have revolutionized the treatment of hematopoietic
malignancies achieving> 50% complete response rates in numerous refractory/relapsed B …

Just as cancer cells were once healthy cells, the body also produces cells that naturally seek
out and destroy cancer cells—aptly named natural killer (NK) cells. As far as immune cells …

Background Due to their powerful immune surveillance activity and ability to kill and clear
cancer cells, natural killer (NK) cells are an emerging anticancer immunotherapeutic agent …

Invariant Natural Killer T cell therapy is an emerging platform of immunotherapy for cancer
treatment. This unique cell population is a promising candidate for cell therapy for cancer …