Artemether is an efficacious antimalarial drug that also displays antischistosomal properties.
Grapefruit juice increases the oral availability of a variety of the CYP3A4 substrates. This …

OBJECTIVE: To investigate immune mechanisms possibly involved in the amelioration of
histopathological changes in livers of Schistosoma mansoni-infected mice treated with …

The drug, artemether, has been shown to be active against the juvenile stages of
Schistosoma japonicum and Schistosoma mansoni in experimentally infected animals, while …

Artemether is an artemisinin derivative that is used as an antimalarial drug, especially in
situations where chloroquine resistance is suspected. This compound has proved to be a …

We investigated the activity of artemether (ART) against different developmental stages of
schistosomes alone and in addition to praziquantel (PZQ). ART was administered orally …

The effect of artemether, an antimalarial drug developed from the plant Artemisia annua, has
been tested against the larval stages of Schistosoma mansoni covering the time from skin …

The current treatment of schistosomiasis is based on the anti-helminthic drug praziquantel
(PZQ). PZQ affects only the adult stages of schistosomes. In addition, resistance to PZQ is …

The current treatment and control of schistosomiasis, rely on a single drug, praziquantel,
although, it has minor activity against juvenile stages of the parasite. Studies have shown …

To determine whether artemether, a derivative of the antimalarial agent qinghaosu, is
therapeutically active against Schistosoma mansoni, we determined the in vitro, in vivo, and …

We recently found that the exposure of schistosomes in vitro to artemether plus haemin can
lead to parasite death, while exposure to each compound singly had no effect. Since these …