Competition between MutY and mismatch repair at A· C mispairs in vivo
M Kim, T Huang, JH Miller - Journal of bacteriology, 2003 - Am Soc Microbiol
We show that the MutY protein competes with the MutS-dependent mismatch repair system
to process at least some A· C mispairs in vivo, converting them to G· C pairs. In the presence …
to process at least some A· C mispairs in vivo, converting them to G· C pairs. In the presence …
Interaction of MutS and Vsr: Some Dominant-NegativemutS Mutations That Disable Methyladenine-Directed Mismatch Repair Are Active in Very-Short-Patch Repair
M Lieb, S Rehmat, AS Bhagwat - Journal of Bacteriology, 2001 - Am Soc Microbiol
In Escherichia coli and related bacteria, the very-short-patch (VSP) repair pathway uses an
endonuclease, Vsr, to correct T· G mismatches that result from the deamination of 5 …
endonuclease, Vsr, to correct T· G mismatches that result from the deamination of 5 …
Deletion mutation analysis of the mutS gene inEscherichia coli
TH Wu, MG Marinus - Journal of Biological Chemistry, 1999 - ASBMB
The MutS protein is part of thedam-directed MutHLS mismatch repair pathway inEscherichia
coli. We have constructed deletion derivatives in the mutS gene, which retain the P-loop …
coli. We have constructed deletion derivatives in the mutS gene, which retain the P-loop …
Mutants with Temperature-Sensitive Defects in the Escherichia coli Mismatch Repair System: Sensitivity to Mispairs Generated In Vivo
ES Hong, A Yeung, P Funchain, MM Slupska… - Journal of …, 2005 - Am Soc Microbiol
We have used direct selections to generate large numbers of mutants of Escherichia coli
defective in the mismatch repair system and have screened these to identify mutants with …
defective in the mismatch repair system and have screened these to identify mutants with …
In vitro and in vivo studies of MutS, MutL and MutH mutants: correlation of mismatch repair and DNA recombination
MS Junop, W Yang, P Funchain, W Clendenin… - DNA repair, 2003 - Elsevier
We have used the recently determined crystal structures of Escherichia coli (E. coli) MutS,
MutL and MutH to guide construction of 47 amino-acid substitutions in these proteins and …
MutL and MutH to guide construction of 47 amino-acid substitutions in these proteins and …
ATP-hydrolysis-dependent conformational switch modulates the stability of MutS–mismatch complexes
The mismatch repair pathway in Escherichia coli has been extensively studied in vitro as
well as in vivo. The molecular mechanisms by which nucleotide cofactors regulate the whole …
well as in vivo. The molecular mechanisms by which nucleotide cofactors regulate the whole …
The MutS C terminus is essential for mismatch repair activity in vivo
MA Calmann, A Nowosielska… - Journal of bacteriology, 2005 - Am Soc Microbiol
An Escherichia coli K-12 strain was constructed with a chromosomal deletion (mutS Δ 800)
in the mutS gene that produced the removal of the C-terminal 53 amino acids which are not …
in the mutS gene that produced the removal of the C-terminal 53 amino acids which are not …
Interaction of Escherichia coli MutS and MutL at a DNA mismatch
MJ Schofield, S Nayak, TH Scott, C Du… - Journal of Biological …, 2001 - ASBMB
MutS and MutL are both required to activate downstream events in DNA mismatch repair.
We examined the rate of dissociation of MutS from a mismatch using linear heteroduplex …
We examined the rate of dissociation of MutS from a mismatch using linear heteroduplex …
Separation of mutation avoidance and antirecombination functions in an Escherichia coli mutS mutant
MA Calmann, A Nowosielska… - Nucleic acids …, 2005 - academic.oup.com
DNA mismatch repair in Escherichia coli has been shown to be involved in two distinct
processes: mutation avoidance, which removes potential mutations arising as replication …
processes: mutation avoidance, which removes potential mutations arising as replication …
Escherichia coli mutY-dependent mismatch repair involves DNA polymerase I and a short repair tract
JJ Tsai-Wu, AL Lu - Molecular and General Genetics MGG, 1994 - Springer
Repair of heteroduplex DNA containing an A/G mismatch in a mutL background requires the
Escherichia coli mutY gene function. The mutY-dependent in vitro repair of A/G mismatches …
Escherichia coli mutY gene function. The mutY-dependent in vitro repair of A/G mismatches …