The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
S Gradia, S Acharya, R Fishel - Cell, 1997 - cell.com
The mechanism of DNA mismatch repair has been modeled upon biochemical studies of the
E. coli DNA adenine methylation–instructed pathway where the initial recognition of …
E. coli DNA adenine methylation–instructed pathway where the initial recognition of …
[引用][C] Mismatch repair systems in Saccharomyces cerevisiae
GF Crouse, JA Nickoloff… - DNA damage …, 1998 - pp. 411ą448. Humana Press Inc …
Stoichiometry of MutS and MutL at unrepaired mismatches in vivo suggests a mechanism of repair
Mismatch repair (MMR) is an evolutionarily conserved DNA repair system, which corrects
mismatched bases arising during DNA replication. MutS recognizes and binds base pair …
mismatched bases arising during DNA replication. MutS recognizes and binds base pair …
DNA mismatch repair: from structure to mechanism
Both MutS and MutL, which are essential for mismatch repair and for ensuring genomic
stability, are conserved in nearly all living organisms (for reviews, see Modrich and Lahue …
stability, are conserved in nearly all living organisms (for reviews, see Modrich and Lahue …
A conserved MutS homolog connector domain interface interacts with MutL homologs
ML Mendillo, VV Hargreaves… - Proceedings of the …, 2009 - National Acad Sciences
Escherichia coli MutS forms a mispair-dependent ternary complex with MutL that is essential
for initiating mismatch repair (MMR) but is structurally uncharacterized, in part owing to its …
for initiating mismatch repair (MMR) but is structurally uncharacterized, in part owing to its …
The C-terminal region of Escherichia coli MutS and protein oligomerization
V Miguel, RJ Pezza, CE Argaraña - Biochemical and biophysical research …, 2007 - Elsevier
Escherichia coli MutS, an 853 amino acids oligomeric protein, is involved in the
postreplicative DNA mismatch repair and avoidance of homeologous recombination. By …
postreplicative DNA mismatch repair and avoidance of homeologous recombination. By …
[HTML][HTML] The alternating ATPase domains of MutS control DNA mismatch repair
MH Lamers, HHK Winterwerp, TK Sixma - The EMBO journal, 2003 - embopress.org
DNA mismatch repair is an essential safeguard of genomic integrity by removing base
mispairings that may arise from DNA polymerase errors or from homologous recombination …
mispairings that may arise from DNA polymerase errors or from homologous recombination …
Role of MutS ATPase activity in MutS, L-dependent block of in vitro strand transfer
L Worth, T Bader, J Yang, S Clark - Journal of Biological Chemistry, 1998 - ASBMB
In addition to mismatch recognition, Escherichia coli MutS has an associated ATPase activity
that is fundamental to repair. Hence, we have characterized two MutS mutant gene products …
that is fundamental to repair. Hence, we have characterized two MutS mutant gene products …
Depletion of the cellular amounts of the MutS and MutH methyl-directed mismatch repair proteins in stationary-phase Escherichia coli K-12 cells
G Feng, HC Tsui, ME Winkler - Journal of bacteriology, 1996 - Am Soc Microbiol
The MutL, MutS, and MutH proteins mediate methyl-directed mismatch (MDM) repair and
help to maintain chromosome stability in Escherichia coli. We determined the amounts of the …
help to maintain chromosome stability in Escherichia coli. We determined the amounts of the …
DNA mismatch repair: MutS structures bound to mismatches
TK Sixma - Current Opinion in Structural Biology, 2001 - Elsevier
When DNA mismatch repair fails, the result is a mutator phenotype, which can lead to cancer
in humans. Functional repair is dependent on the recognition of mismatches by a dimeric …
in humans. Functional repair is dependent on the recognition of mismatches by a dimeric …