[图书][B] Quantitative in vivo imaging of tissue absorption, scattering, and hemoglobin concentration in rat cortex using spatially modulated structured light

DJ Cuccia, D Abookasis, RD Frostig, BJ Tromberg - 2009 - escholarship.org
Significant changes in blood flow or in the integrity of cerebral vessels are believed to cause
cerebrovascular disease (CVD) and to contribute to dementias including Alzheimer's …

Improving the diffuse optical imaging spatial resolution of the cerebral hemodynamic response to brain activation in humans

DA Boas, K Chen, D Grebert, MA Franceschini - Optics letters, 2004 - opg.optica.org
We compare two geometries of sources and detectors for optimizing the diffuse optical
imaging resolution of brain activation in humans. Because of limitations in the instruments' …

Transcranial diffuse optical monitoring of microvascular cerebral hemodynamics after thrombolysis in ischemic stroke

P Zirak, R Delgado-Mederos, L Dinia… - … of biomedical optics, 2014 - spiedigitallibrary.org
The ultimate goal of therapeutic strategies for ischemic stroke is to reestablish the blood flow
to the ischemic region of the brain. However, currently, the local cerebral hemodynamics …

Direct characterization and removal of interfering absorption trends in two-layer turbid media

RB Saager, AJ Berger - JOSA A, 2005 - opg.optica.org
We propose a method to isolate absorption trends confined to the lower layer of a two-layer
turbid medium, as is desired in near-infrared spectroscopy (NIRS) of cerebral …

Simulation study of magnetic resonance imaging–guided cortically constrained diffuse optical tomography of human brain function

DA Boas, AM Dale - Applied optics, 2005 - opg.optica.org
Diffuse optical imaging can measure brain activity noninvasively in humans through the
scalp and skull by measuring the light intensity modulation arising from localized-activity …

Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation

T Durduran, G Yu, MG Burnett, JA Detre… - Optics letters, 2004 - opg.optica.org
We combine diffuse optical and correlation spectroscopies to simultaneously measure the
oxyhemoglobin and deoxyhemoglobin concentration and blood flow in an adult human …

Diffuse optics for tissue monitoring and tomography

T Durduran, R Choe, WB Baker… - Reports on progress in …, 2010 - iopscience.iop.org
This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

Image reconstruction of oxidized cerebral cytochrome C oxidase changes from broadband near-infrared spectroscopy data

S Brigadoi, P Phan, D Highton, S Powell… - …, 2017 - spiedigitallibrary.org
In diffuse optical tomography (DOT), overlapping and multidistance measurements are
required to reconstruct depth-resolved images of oxy-(HbO 2) and deoxy-(HHb) hemoglobin …

Transcranial Doppler and near-infrared spectroscopy can evaluate the hemodynamic effect of carotid artery occlusion

F Vernieri, F Tibuzzi, P Pasqualetti, N Rosato… - Stroke, 2004 - Am Heart Assoc
Background and Purpose—Cerebral hemodynamic and metabolic changes can
compensate for the decrease in cerebral blood flow occurring in patients with carotid …

Imaging of cortical oxygen tension and blood flow following targeted photothrombotic stroke

CT Sullender, AE Mark, TA Clark, TV Esipova… - …, 2018 - spiedigitallibrary.org
We present a dual-modality imaging system combining laser speckle contrast imaging and
oxygen-dependent quenching of phosphorescence to simultaneously map cortical blood …