Complementary diversification of dendritic cells and innate lymphoid cells

CG Briseño, TL Murphy, KM Murphy - Current opinion in immunology, 2014 - Elsevier
Highlights•Transcriptional requirements of DC subset development.•Batf3-dependent
CD8α+ DCs mediate type I immune responses.•CD11b+ DCs orchestrate ILC3 and TH 17 …

Transcriptional control of dendritic cell development

KM Murphy - Advances in immunology, 2013 - Elsevier
Dendritic cells (DCs) drive both adaptive and innate immunity. Recent findings support the
notion that distinct subsets of classical DCs favor alternative modules of immunity, acting on …

Dendritic cell lineage, plasticity and cross-regulation

YJ Liu, H Kanzler, V Soumelis, M Gilliet - Nature immunology, 2001 - nature.com
Dendritic cells (DCs) are professional antigen-presenting cells that have an extraordinary
capacity to stimulate naïve T cells and initiate primary immune responses. Here we review …

Transcriptional networks driving dendritic cell differentiation and function

SL Nutt, M Chopin - Immunity, 2020 - cell.com
Dendritic cells (DCs) are the sentinels of the immune system, sensing a diverse array of
pathogens to stimulate a robust and appropriate immune response. To initiate responses to …

Innate control of adaptive immunity: dendritic cells and beyond

HK Lee, A Iwasaki - Seminars in immunology, 2007 - Elsevier
Innate immune recognition of pathogens triggers both immediate defenses against the
invading pathogens and the initiation of adaptive immune responses. Dendritic cells (DCs) …

Signal transduction in DC differentiation: winged messengers and Achilles' heel

I Lindner, PJ Cejas, LM Carlson, J Torruellas… - … between Innate and …, 2007 - Springer
Dendritic cells (DC) are centrally involved in the initiation and regulation of the adaptive
immune response, and different DC can have markedly different (eg, opposing) function …

Dendritic cell regulation of T helper cells

X Yin, S Chen, SC Eisenbarth - Annual review of immunology, 2021 - annualreviews.org
As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …

Transcriptional regulation of dendritic cell diversity

M Chopin, RS Allan, GT Belz - Frontiers in immunology, 2012 - frontiersin.org
Dendritic cells (DCs) are specialized antigen presenting cells that are exquisitely adapted to
sense pathogens and induce the development of adaptive immune responses. They form a …

Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming

M Dalod, R Chelbi, B Malissen, T Lawrence - The EMBO journal, 2014 - embopress.org
Dendritic cells (DC) are key regulators of both protective immune responses and tolerance
to self‐antigens. Soon after their discovery in lymphoid tissues by Steinman and Cohn, as …

Shared transcriptional control of innate lymphoid cell and dendritic cell development

P Bagadia, X Huang, TT Liu… - Annual review of cell and …, 2019 - annualreviews.org
Innate immunity and adaptive immunity consist of highly specialized immune lineages that
depend on transcription factors for both function and development. In this review, we dissect …