Complementary diversification of dendritic cells and innate lymphoid cells
CG Briseño, TL Murphy, KM Murphy - Current opinion in immunology, 2014 - Elsevier
Highlights•Transcriptional requirements of DC subset development.•Batf3-dependent
CD8α+ DCs mediate type I immune responses.•CD11b+ DCs orchestrate ILC3 and TH 17 …
CD8α+ DCs mediate type I immune responses.•CD11b+ DCs orchestrate ILC3 and TH 17 …
Transcriptional control of dendritic cell development
KM Murphy - Advances in immunology, 2013 - Elsevier
Dendritic cells (DCs) drive both adaptive and innate immunity. Recent findings support the
notion that distinct subsets of classical DCs favor alternative modules of immunity, acting on …
notion that distinct subsets of classical DCs favor alternative modules of immunity, acting on …
Dendritic cell lineage, plasticity and cross-regulation
Dendritic cells (DCs) are professional antigen-presenting cells that have an extraordinary
capacity to stimulate naïve T cells and initiate primary immune responses. Here we review …
capacity to stimulate naïve T cells and initiate primary immune responses. Here we review …
Transcriptional networks driving dendritic cell differentiation and function
Dendritic cells (DCs) are the sentinels of the immune system, sensing a diverse array of
pathogens to stimulate a robust and appropriate immune response. To initiate responses to …
pathogens to stimulate a robust and appropriate immune response. To initiate responses to …
Innate control of adaptive immunity: dendritic cells and beyond
Innate immune recognition of pathogens triggers both immediate defenses against the
invading pathogens and the initiation of adaptive immune responses. Dendritic cells (DCs) …
invading pathogens and the initiation of adaptive immune responses. Dendritic cells (DCs) …
Signal transduction in DC differentiation: winged messengers and Achilles' heel
I Lindner, PJ Cejas, LM Carlson, J Torruellas… - … between Innate and …, 2007 - Springer
Dendritic cells (DC) are centrally involved in the initiation and regulation of the adaptive
immune response, and different DC can have markedly different (eg, opposing) function …
immune response, and different DC can have markedly different (eg, opposing) function …
Dendritic cell regulation of T helper cells
As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …
Transcriptional regulation of dendritic cell diversity
Dendritic cells (DCs) are specialized antigen presenting cells that are exquisitely adapted to
sense pathogens and induce the development of adaptive immune responses. They form a …
sense pathogens and induce the development of adaptive immune responses. They form a …
Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming
Dendritic cells (DC) are key regulators of both protective immune responses and tolerance
to self‐antigens. Soon after their discovery in lymphoid tissues by Steinman and Cohn, as …
to self‐antigens. Soon after their discovery in lymphoid tissues by Steinman and Cohn, as …
Shared transcriptional control of innate lymphoid cell and dendritic cell development
Innate immunity and adaptive immunity consist of highly specialized immune lineages that
depend on transcription factors for both function and development. In this review, we dissect …
depend on transcription factors for both function and development. In this review, we dissect …