Alzheimer's disease (AD) is a complex disorder with unknown etiology. Currently, only
symptomatic therapy of AD is available, comprising cholinesterase inhibitors and N-methyl-d …

Background: With the burgeoning worldwide aging population, the incidence of Alzheimer's
disease (AD) and its associated disorders is continuously rising. To appraise other relevant …

Alzheimer's disease (AD) is a complex disease with an unknown etiology. Available
treatments, limited to cholinesterase inhibitors and N-methyl-d-aspartate receptor (NMDAR) …

Alzheimer's disease (AD) is a neurodegenerative disorder representing the leading cause of
dementia and is affecting nearly 44 million people worldwide. AD is characterized by a …

Alzheimer's disease is a common and most chronic neurological disorder (NDs) associated
with cognitive dysfunction. Pathologically, Alzheimer's disease (AD) is characterized by the …

For the potential therapy of Alzheimer's disease (AD), butyrylcholinesterase (BChE) has
gradually gained worldwide interest in the progression of AD. This study used a …

Alzheimer's disease (AD) is a multifactorial and progressive neurodegenerative disease,
associated with aging. A total of forty benzylidene‐indenone derivatives were synthesized in …

Optimization and re-optimization of bioactive molecules using in silico methods have found
application in the design of more active ones. Herein, we applied a pharmacophore …

Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of
dementia worldwide. It is characterized by a progressive decline in cholinergic …

In this article, we present the design and synthesis of amino-7, 8-dihydro-4H-chromenone
derivatives as possible inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase …