Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder

N Yoshimura - Progress in neurobiology, 1999 - Elsevier
Lower urinary tract dysfunction is a common problem in patients with spinal cord injury (SCI).
Since the coordination of the urinary bladder and urethra is controlled by the complex …

Effects of acute sacral neuromodulation on bladder reflex in complete spinal cord injury rats

P Shi, X Zhao, J Wang, N Lan - Neuromodulation: Technology at the Neural …, 2013 - Elsevier
Background Neurogenic bladder associated with spinal cord injury (SCI) often results in
serious disruption of lower urinary tract function. Compared to conventional therapies, sacral …

Urinary bladder response to hypogastric nerve stimulation after bilateral resection of the pelvic nerve or spinal cord injury in rats

H Kontani, K Hayashi - International journal of urology, 1997 - Wiley Online Library
Background: We examined the mechanism of urinary bladder motility return after bladder
areflexia induced by interruption of the sacral parasympathetic outflow to the urinary bladder …

A noninvasive ultrasonographic method to evaluate bladder function recovery in spinal cord injured rats

HS Keirstead, V Fedulov, F Cloutier, O Steward… - Experimental …, 2005 - Elsevier
Suprasacral spinal cord injury induces changes in the mechanical and neuronal properties
of the bladder resulting in bladder areflexia followed by bladder–sphincter dyssynergia and …

Mapping and neuromodulation of lower urinary tract function using spinal cord stimulation in female rats

HH Chang, JC Yeh, RM Ichiyama, LV Rodriguez… - Experimental …, 2018 - Elsevier
Spinal cord epidural stimulation (SCS) represents a form of neuromodulation for the
management of spasticity and pain. This technology has recently emerged as a new …

Sprouting of CGRP primary afferents in lumbosacral spinal cord precedes emergence of bladder activity after spinal injury

NDT Zinck, VF Rafuse, JW Downie - Experimental neurology, 2007 - Elsevier
Spinal cord injury (SCI) severely disrupts bladder function. What mediates bladder
dysfunction after SCI is currently unknown. We investigated the role that primary afferent …

Immortalized neural stem cells transplanted into the injured spinal cord promote recovery of voiding function in the rat

T Mitsui, H Kakizaki, H Tanaka, T Shibata… - The Journal of …, 2003 - Elsevier
PURPOSE: Bladder dysfunction is a serious consequence of spinal cord injury. Cellular
transplantation into the injured spinal cord can promote axonal growth and functional …

TGF‐β1 and connexin‐43 expression in neurogenic bladder from rats with sacral spinal cord injury

J Zhao, M Wu, S Chen, Z Ji… - Neurourology and …, 2018 - Wiley Online Library
Aims Sacral spinal cord injury (SCI) could induce underactive bladder (UAB). Malfunction of
connexin 43 (CX43) regulated by TGF‐β1 might involve in urinary bladder dysfunction. We …

Neurogenic bladder model for spinal cord injury: spinal cord microdialysis and chronic urodynamics

CP Smith, GT Somogyi, ET Bird, MB Chancellor… - Brain research …, 2002 - Elsevier
We describe an animal model to study neurotransmitter changes in parallel with urodynamic
testing following Spinal Cord Injury (SCI). Urodynamic access was achieved using a …

Antifibrosis treatment by inhibition of VEGF, FGF, and PDGF receptors improves bladder wall remodeling and detrusor overactivity in association with modulation of C …

J Kwon, EJ Lee, HJ Cho, JA Jang… - Neurourology and …, 2021 - Wiley Online Library
Aims Spinal cord injury (SCI) above the sacral level causes bladder dysfunction and
remodeling with fibrosis. This study examined the antifibrotic effects using nintedanib, an …