Neurogenic bladder in spinal cord injury patients

WA Taweel, R Seyam - Research and reports in urology, 2015 - Taylor & Francis
Neurogenic bladder dysfunction due to spinal cord injury poses a significant threat to the
well-being of patients. Incontinence, renal impairment, urinary tract infection, stones, and …

Suppression of detrusor-sphincter dyssynergia by immunoneutralization of nerve growth factor in lumbosacral spinal cord in spinal cord injured rats

S Seki, K Sasaki, Y Igawa, O Nishizawa… - The Journal of …, 2004 - auajournals.org
Purpose: We investigated the effects of intrathecal application of nerve growth factor (NGF)
antibodies (NGF-Abs) and desensitization of C-fiber afferent pathways by capsaicin …

[HTML][HTML] Transplantation and repair: combined cell implantation and chondroitinase delivery prevents deterioration of bladder function in rats with complete spinal cord …

K Fouad, DD Pearse, W Tetzlaff, R Vavrek - Spinal Cord, 2009 - nature.com
Study design: Additional examination. In this study, we report changes in bladder function
after a combined treatment that was designed to study axonal regeneration after complete …

[HTML][HTML] The effect of mesenchymal stem cell transplantation on the recovery of bladder and hindlimb function after spinal cord contusion in rats

WB Park, SY Kim, SH Lee, HW Kim, JS Park… - BMC neuroscience, 2010 - Springer
Background Mesenchymal stem cells are widely used for transplantation into the injured
spinal cord in vivo model and for safety, many human clinical trials are continuing to promote …

[HTML][HTML] Peripheral nerve transplantation combined with acidic fibroblast growth factor and chondroitinase induces regeneration and improves urinary function in …

MA DePaul, CY Lin, J Silver, YS Lee - PloS one, 2015 - journals.plos.org
The loss of lower urinary tract (LUT) control is a ubiquitous consequence of a complete
spinal cord injury, attributed to a lack of regeneration of supraspinal pathways controlling the …

[HTML][HTML] Slow development of bladder malfunction parallels spinal cord fiber sprouting and interneurons' loss after spinal cord transection

AM Sartori, AS Hofer, MI Scheuber, R Rust… - Experimental …, 2022 - Elsevier
Neurogenic lower urinary tract dysfunction typically develops after spinal cord injury. We
investigated the time course and the anatomical changes in the spinal cord that may be …

Neurochemical plasticity and the role of neurotrophic factors in bladder reflex pathways after spinal cord injury

MA Vizzard - Progress in brain research, 2006 - Elsevier
Transection of the spinal cord that interrupts the spinobulbospinal micturition reflex pathway,
abolishes voluntary voiding and initially produces an areflexic bladder with complete urinary …

[HTML][HTML] Current knowledge and novel frontiers in lower urinary tract dysfunction after spinal cord injury: Basic research perspectives

N Wada, S Karnup, K Kadekawa, N Shimizu… - Urological …, 2022 - journals.lww.com
This review article aims to summarize the recent advancement in basic research on lower
urinary tract dysfunction (LUTD) following spinal cord injury (SCI) above the sacral level. We …

Changes in afferent activity after spinal cord injury

WC de Groat, N Yoshimura - Neurourology and Urodynamics …, 2010 - Wiley Online Library
Aims To summarize the changes that occur in the properties of bladder afferent neurons
following spinal cord injury. Methods Literature review of anatomical, immunohistochemical …

Effect of urinary diversion on the recovery of micturition reflexes after spinal cord injury in the rat

MN Kruse, B Bennett, WC De Groat - The Journal of urology, 1994 - Elsevier
Patients with suprasacral spinal cord injury usually exhibit severe lower urinary tract
dysfunction, which is generally attributed to loss of supraspinal input to the spinal micturition …