Epigenetic alterations, including changes in DNA methylation, histone modifications and
nucleosome remodeling, result in abnormal gene expression patterns that contribute to …

During cancer development and progression, tumor cells undergo abnormal epigenetic
modifications, including DNA methylation, histone deacetylation and nucleosome …

Highlights•Patients who receive antiandrogen treatments are more likely to develop
CRPC.•A genomic landscape study has identified aberrant epigenetic events in CRPC and …

Simple Summary Chromatin and epigenetic alterations in cancer are responsible for a wide
range of transcriptional changes that link DNA mutations to tumor phenotype. In this review …

Context In addition to genetic alterations, epigenetic alterations play a crucial role during
prostate cancer progression. A better understanding of the epigenetic factors that promote …

Abstract Purpose of Review An important number of newly identified molecular alterations in
prostate cancer affect gene encoding master regulators of chromatin biology epigenetic …

Epigenetics is the main mechanism that controls transcription of specific genes with no
changes in the underlying DNA sequences. Epigenetic alterations lead to abnormal gene …

Prostate cancer is a commonly diagnosed cancer in men and a leading cause of cancer
deaths. Whilst the underlying mechanisms leading to prostate cancer are still to be …

Prostate cancer is the most common noncutaneous malignancy and the second leading
cause of cancer death among men in the United States. DNA methylation and histone …

Prostate cancer (PC) is the most commonly diagnosed nonskin malignancy and the second
most common cause of cancer death among men in the United States. Epigenetics is the …