Tricyclic antidepressant (TCA) drugs are also used as adjunctive therapy to treat chronic
pain. To monitor patient compliance to therapy, urine specimens may be preferred since …

Tricyclic antidepressants have been prescribed for the treatment of depression and other
disorders since their discovery in the 1950s but have been replaced in recent decades by …

A sensitive, specific, and rapid high‐pressure liquid chromatography/mass
spectrometry/mass spectrometry method was developed for the quantitation of 11 tricyclic …

Patients taking tricyclic antidepressants (TCA) can experience toxicity or severe side effects.
As a rapid and less technically demanding alternative to quantitative serum analysis, most …

The body of evidence gained up to date is sufficient to indicate that high-pressure liquid
chromatography (LC) has versatility and sensitivity in abundance for analyzing tricyclic …

Depression is a psychiatric condition that affects about 120 million people worldwide and
can interfere with independence and productivity in essentially all aspects of daily life …

An analytical procedure has been developed for the simultaneous separation and
quantitation of amitriptyline (AMI), imipramine (IMI), doxepin (DOX), trimipramine (TRI) …

The EMITtox serum tricyclic antidepressant (TCA) assay is intended for use with serum or
plasma. Currently, there are no commercially available immunoassay kits available for the …

Purpose To quantify the effect of clinical and demographic factors on the risk of elevated and
toxic tricyclic antidepressant (TCA) plasma concentrations (Cp) and to describe the rates of …

A HPLC method has been developed for the simultaneous determination of seven tricyclic
antidepressants (TCAs) and seven metabolites in human plasma. The analyte separation …