Case 1. Patient 1 is a 65-year-old plumber who presents with fatigue, headache, blurred
vision, and intermittent nosebleeds for the past 3 months. Examination demonstrates mild …

Plasma hyperviscosity is a rare complication of both monoclonal and polyclonal disorders
associated with elevation of immunoglobulins. Asymptomatic patients with an elevation in …

Whole blood viscosity is affected by a number of factors, among which plasma proteins are a
major component. They exert their effects either directly or through their influence on red cell …

Hypergammaglobulinemia increases serum viscosity and is the most common cause of
hyperviscosity syndrome. Monoclonal hypergammaglobulinemia resulting in hyperviscosity …

Hyperviscosity syndrome is a serious complication associated with high levels of
paraproteins in patients with hematological malignancies. Therapeutic advances in disease …

For a considerable time, hyperviscosity syndrome has been widely recognized as a serious
manifestation of polycythemia and plasma cell dyscrasia. In this article a number of …

This article discusses the fundamentals for measuring the viscosity of whole blood, serum,
and plasma and its application to the diagnosis of hyperviscosity syndrome. We describe …

Therapeutic apheresis (TA), as a way of rapidly eliminating harmful or excessive blood
components such as plasma proteins (plasma exchange) or cells (leukapheresis and …

One of the most striking complications in hematologic disease is the development of acute
blood hyperviscosity. Classically, hyperviscosity presents with the triad of bleeding, visual …

Therapeutic plasma exchange is an extra-corporeal technique able to remove from blood
macromolecules and/or replace deficient plasma factors. It is the treatment of choice in …