Immunoglobulin G (IgG) is the predominant component in humoral immunity and the major
effector of neutralizing heterogeneous antigens. Glycosylation, as excessive …

Abstract Changes in immunoglobulin G (IgG) glycan structures are currently believed to
closely related to the emergence of cancer. In this review, we summarize the current body of …

Cancer is prevalent worldwide. Currently, most routinely used non-invasive serological
cancer biomarkers, including carcino-embryonic antigen (CEA), prostate-specific antigen …

Glycosylation and its by-product, the glycan, play a crucial role in many cellular processes.
Aberrant glycan structures and mutations of the glycosylation pathway have been intricately …

This review provides insights on the impact of glycosylation in cancer biology and its
influence in the current approaches of targeted cancer therapies in the clinical setting. The …

Glycosylation is an important post-translational modification, giving rise to a diverse and
abundant repertoire of glycans on the cell surface, collectively known as the glycome. When …

Immunotherapy has shown great potential in cancer treatment. However, even with the
intervention of techniques such as immune checkpoint inhibitor therapy, tumors can still …

Simple Summary Glycosylation is one of the most pivotal post-translational modifications on
all types of biomolecules for the formation of glycoproteins, glycolipids, and glycoRNAs in a …

Aberrant cell surface glycosylation signatures are currently known to actively drive the
neoplastic transformation of healthy cells. By disrupting the homeostatic functions of their …

Glycans are part of the essential components of a cell. These compounds play a
fundamental role in several physiopathological processes, including cell differentiation …