Lung accumulation of hyaluronan parallels pulmonary edema in experimental alveolitis

O Nettelbladt, A Tengblad… - American Journal of …, 1989 - journals.physiology.org
The glycosaminoglycan hyaluronan (HA, hyaluronate or hyaluronic acid) was quantified in
rat lung during the development of bleomycin-induced lung injury. Extracted lung HA was …

High-dose corticosteroids during bleomycin-induced alveolitis in the rat do not suppress the accumulation of hyaluronan (hyaluronic acid) in lung tissue

O Nettelbladt, A Tengblad… - European Respiratory …, 1990 - Eur Respiratory Soc
A single intratracheal injection of bleomycin in rats induced, 4 days later, a considerable
accumulation of hyaluronan (hyaluronate, hyaluronic acid) in the lung tissue. This …

Accumulation of hyaluronic acid in the alveolar interstitial tissue in bleomycin-induced alveolitis.

O Nettelbladt, J Bergh, M Schenholm… - American Journal of …, 1989 - atsjournals.org
By using biotin-labeled proteoglycan core protein and an aVidin-enzyme system, hyaluronic
acid (HA) was visualized in the lungs of rats at different times (4, 10, and 20 days) after …

Early changes in lung tissue hyaluronan (hyaluronic acid) and hyaluronidase in bleomycin-induced alveolitis in hamsters

BA Bray, PM Sampson, M Osman… - Am Rev Respir …, 1991 - atsjournals.org
Early Changes in Lung Tissue Hyaluronan (Hyaluronic Acid) and Hyaluronidase in
Bleomycin-induced Alveolitis in Hamsters Page 1 Early Changes in Lung Tissue …

A role for hyaluronan in macrophage accumulation and collagen deposition after bleomycin-induced lung injury

RC Savani, G Hou, P Liu, C Wang… - American journal of …, 2000 - atsjournals.org
Elevated concentrations of hyaluronan (HA) are associated with the accumulation of
macrophages in the lung after injury. We have investigated the role of HA in the …

Hyaluronan(hyaluronic acid) in bronchoalveolar lavage fluid during the development of bleomycin-induced alveolitis in the rat.

O Nettelbladt, R Hällgren - … Journal of Respiratory and Critical Care …, 1989 - atsjournals.org
Hyaluronan (Hyaluronic Acid) in Bronchoalveolar Lavage Fluid during the Development of
Bleomycin-induced Alveolitis in the Rat Page 1 Hyaluronan (Hyaluronic Acid) in …

Characterization of the mechanism involved in bleomycin-induced increased hyaluronan production in rat lung.

P Teder, O Nettelbladt, P Heldin - American journal of respiratory …, 1995 - atsjournals.org
The molecular mechanisms behind the accumulation of hyaluronan during bleomycin-
induced lung injury in rats were investigated. The stimulatory effects of bronchoalveolar …

Mechanism of impaired local hyaluronan turnover in bleomycin-induced lung injury in rat

P Teder, P Heldin - American journal of respiratory cell and …, 1997 - atsjournals.org
Hyaluronan, a linear polysaccharide, is accumulated in lung interstitium during different
pathological conditions, causing interstitial edema and thereby impaired lung function. We …

[HTML][HTML] Hyaluronan in respiratory injury and repair

GM Turino, JO Cantor - American journal of respiratory and critical …, 2003 - atsjournals.org
Over the past two decades, much of the research on the cellular hyaluronic acid as the
terminology. HA is a naturally occurring, and biochemical reactions to injurious agents of the …

Alveolar accumulation of hyaluronan and alveolar cellular response in bleomycin-induced alveolitis

O Nettelbladt, A Scheynius, J Bergh… - European …, 1991 - Eur Respiratory Soc
Hyaluronan (HA) accumulating in the alveolar interstitial tissue of rats injured by a single
intratracheal instillation of bleomycin has been visualized histologically and assayed. HA …