Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay.

MJ Bevan - The Journal of experimental medicine, 1976 - rupress.org
Cytotoxic effector T cells of F1 (BALB/c X BALB. B)(H-2d/b) mice immunized against the
minor histocompatibility differences of C57BL/10 (H-2b) can lyse targets from C57BL/10, but …

The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigens.

MJ Bevan - The Journal of experimental medicine, 1975 - rupress.org
Cytotoxic cells were generated by immunizing one strain of mouse with cells from an
allogeneic strain which carries the same H-2 region. The effector cells assayed in a 4 h 51Cr …

H-2 antigens of the thymus determinelymphocyte specificity

PJ Fink, MJ Bevan - The Journal of experimental medicine, 1978 - rupress.org
After immunization, normal H-2 heterozygous mice (for example H-2 (b)× H-2 (d)) generate
two populations of cytotoxic effector T cells, one specific for target cells expressing H-2 (b) …

Induction of H-2-restricted cytotoxic T cells: in vivo induction has the appearance of being unrestricted

P Matzinger, MJ Bevan - Cellular Immunology, 1977 - Elsevier
The effector function of cytotoxic T cells specific for minor histocompatibility antigens in mice
is restricted by the H-2 gene complex. We report here, however, that the in vivo induction of …

Minor H antigens introduced on H-2 different stimulating cells cross-react at the cytotoxic T cell level during in vivo priming

MJ Bevan - The Journal of Immunology, 1976 - journals.aai.org
The cellular basis of the cross-priming observed with minor histocompatibility antigens on H-
2 different cells was investigated. Cytotoxic T cells induced against minor alloantigens show …

Antigen recognition by cloned cytotoxic T lymphocytes follows rules predicted by the altered-self hypothesis.

TR Hünig, MJ Bevan - The Journal of experimental medicine, 1982 - rupress.org
Radiation chimeras prepared by injecting H-2 heterozygous F1 stem cells into lethally
irradiated parental hosts show a marked, but not absolute, preference for host-type H-2 …

On the role of the H-2 histocompatibility complex in determining the specificity of cytotoxic effector cells sensitized against syngeneic trinitrophenyl-modified targets.

J Forman - The Journal of experimental medicine, 1975 - rupress.org
Spleen cells cultured with syngeneic trinitrophenyl (TNP)-modified stimulator cells display a
cytotoxic effect against syngeneic TNP-modified targets, but not against modified targets …

Killer cells reactive to altered-self antigens can also be alloreactive.

MJ Bevan - Proceedings of the National Academy of …, 1977 - National Acad Sciences
Murine cytotoxic thymus-derived lymphocytes immunized against cells bearing foreign minor
histocompatibility antigens are specific for the immunizing minor antigens and for their own …

Histocompatibility antigen-activated cytotoxic T lymphocytes. II. Estimates of the frequency and specificity of precursors.

KF Lindahl, DB Wilson - The Journal of experimental medicine, 1977 - rupress.org
Using limiting dilutions of responding cells in mouse mixed leukocyte cultures, we obtained
direct estimates of the minimum frequency of precursors of cytotoxic T lymphocytes (CTL. P) …

Induction of cytotoxic T lymphocytes against I-region-coded determinants: in vitro evidence for a third histocompatibility locus in the mouse.

H Wagner, D Götze, L Ptschelinzew… - The Journal of …, 1975 - rupress.org
Determinants controlled by the I region of the murine H-2 complex provoked the generation
of cytotoxic T lymphocytes (CTL) in both a secondary and primary mixed lymphocyte culture …