Cloning and characterization of chicken IL-10 and its role in the immune response to Eimeria maxima

L Rothwell, JR Young, R Zoorob… - The Journal of …, 2004 - journals.aai.org
We isolated the full-length chicken IL-10 (chIL-10) cDNA from an expressed sequence tag
library derived from RNA from cecal tonsils of Eimeria tenella-infected chickens. It encodes a …

Isolation and characterization of chicken interleukin-17 cDNA

W Min, HS Lillehoj - Journal of interferon & cytokine research, 2002 - liebertpub.com
Interleukin-17 (IL-17) is a proinflammatory cytokine produced by activated T cells. A 917-bp
cDNA encoding the IL-17 gene was isolated from our EST cDNA library prepared from …

[HTML][HTML] Analysis of the function of IL-10 in chickens using specific neutralising antibodies and a sensitive capture ELISA

Z Wu, T Hu, L Rothwell, L Vervelde, P Kaiser… - Developmental & …, 2016 - Elsevier
In mammals, the inducible cytokine interleukin 10 is a feedback negative regulator of
inflammation. To determine the extent to which this function is conserved in birds …

Identification and molecular cloning of functional chicken IL-12

WGJ Degen, N van Daal, HI van Zuilekom… - The Journal of …, 2004 - journals.aai.org
By a combination of large-scale sequencing, bioinformatics, and traditional molecular
biology, we identified the long-searched-for cDNA sequences encoding the homologues of …

Molecular, cellular, and functional characterization of chicken cytokines homologous to mammalian IL-15 and IL-2

HS Lillehoj, W Min, KD Choi, US Babu… - Veterinary immunology …, 2001 - Elsevier
DNA sequence analysis of a chicken interleukin (IL)-15 cDNA identified a 187 amino acid
open reading frame encoding a protein with a predicted molecular weight of 21,964 Da, two …

Recent progress in host immunity to avian coccidiosis: IL-17 family cytokines as sentinels of the intestinal mucosa

W Min, WH Kim, EP Lillehoj, HS Lillehoj - Developmental & Comparative …, 2013 - Elsevier
The molecular and cellular mechanisms leading to immune protection against coccidiosis
are complex and include multiple aspects of innate and adaptive immunities. Innate …

Cloning, expression and initial characterisation of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)

G Gallagher, H Dickensheets, J Eskdale, LS Izotova… - Genes & …, 2000 - nature.com
Abstract Interleukin-10 (IL-10) is a pleiotropic cytokine with important immunoregulatory
functions whose actions influence activities of many of the cell-types in the immune system …

Recent progress on the cytokine regulation of intestinal immune responses to Eimeria

HS Lillehoj, W Min, RA Dalloul - Poultry Science, 2004 - Elsevier
A variety of methods are available to combat avian diseases in the commercial setting,
including improved farm management practices, use of antibiotic drugs, selection of disease …

In Vivo Effects of Chicken Interferon-γ During Infection with Eimeria

JW LOWENTHAL, JJ YORK, TE O'NEIL… - Journal of interferon & …, 1997 - liebertpub.com
Newly hatched chickens are highly susceptible to infection by opportunistic pathogens
during the first 1 or 2 weeks of life. The use of cytokines as therapeutic agents has been …

Changes in immune-related gene expression and intestinal lymphocyte subpopulations following Eimeria maxima infection of chickens

YH Hong, HS Lillehoj, EP Lillehoj, SH Lee - Veterinary immunology and …, 2006 - Elsevier
Coccidiosis, a major intestinal parasitic disease of poultry, induces a cell-mediated immune
response against the etiologic agent of the disease, Eimeria. In the current study, the …