Background Andrographolide (AD) has been reported to play a potential anti-arthritic role by
facilitating the proliferation and inhibiting the apoptosis of chondrocytes. However, the …

Background Synovial inflammation plays a major role in the pathogenesis of osteoarthritis
(OA). This study investigated the effect of andrographolide (Andro) on synovial inflammation …

Background As a potential anti‐arthritic agent, Andrographolide (And) is capable of
promoting chondrocyte proliferation and preventing apoptosis in pathologic condition. The …

Recent studies have shown that andrographolide (AP) has the potential to be developed as
a drug for therapy for osteoarthritis (OA). However, the role of AP in attenuating the …

Andrographolide (AD) is the main compound distributed in medicinal herb Andrographis
paniculata and exhibits anti-inflammatory activity. AD has been used for the treatment of …

Objective Our purpose is to unveil Andrographolide's potential multi-target and multi-
mechanism therapeutic effects in treating OA via systematic network pharmacological …

As the main active constituent of Andrographis paniculata that was applied in treatment of
many diseases including inflammation in ancient China, andrographolide (ANDRO) was …

Objective The aim of this study was to investigate the effects of andrographolide on matrix
metalloproteinases (MMP) 1, 3, and 13 and inducible nitric oxide synthase (iNOS) in human …

Ethnopharmacological relevance Traditional plant-derived medicines have enabled the
mankind in curing the wide spectrum of diseases throughout the ages. Andrographis …

The pseudo-tumoral expansion of fibroblast-like synoviocytes is a hallmark of rheumatoid
arthritis (RA), and targeting rheumatoid arthritis fibroblast-like synoviocytes (RAFLSs) may …