Background The increasing multiple sclerosis (MS) prevalence is varying across the
macroscopic regional areas. Only few studies have explored the microscopic geographic …

Abstract Tuscany (Central Italy) is a high-risk area for multiple sclerosis (MS) with a
prevalence of 188 cases per 100,000 at 2011, and it is characterized by a heterogeneous …

Background: Previous studies, dating back to the 1960s disclosed a progressive increase in
multiple sclerosis (MS) incidence and prevalence in the Province of Padua. To further …

We carried out an ecological study in the most archaic area of Sardinia to obtain a reliable
estimate of the prevalence of multiple sclerosis (MS) and to investigate the geographical …

Italy is definitely a high-risk country for multiple sclerosis (MS). Over the last 50 years,
several epidemiological studies, including longitudinal surveys, have disclosed that MS …

MS is a disorder of the central nervous system, manifesting as acute focal inflammatory
demyelination and axonal loss, and culminating with chronic multifocal sclerotic plaques …

Background: Epidemiological studies conducted in Sicily and Sardinia, the two major
Mediterranean islands, showed elevated incidence and prevalence of multiple sclerosis …

Background: To what extent the progressive increase in the incidence of multiple sclerosis
(MS) observed in the province of Padova over the period 1970–1999 was an expression of a …

Background: The prevalence of multiple sclerosis varies considerably throughout the world.
Objective: To better define the prevalence of MS in central Italy. Methods: This is a …

Background: To assess a longitudinal follow-up of the prevalence of multiple sclerosis (MS)
through 4 decades in the province of Ferrara, northern Italy, and reappraise the current rates …