Frequent detection of minimal residual disease by use of the polymerase chain reaction in long-term survivors after bone marrow transplantation for chronic myeloid …

JM Pignon, T Henni, S Amselem, M Vidaud… - Leukemia, 1990 - europepmc.org
The polymerase chain reaction (PCR) allows the detection of minimal amounts of nucleic
sequences and has been successfully used to test for the chronic myeloid leukemia-specific …

Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction.

CL Sawyers, L Timson, ES Kawasaki… - Proceedings of the …, 1990 - National Acad Sciences
Relapse of chronic myelogenous leukemia after bone marrow transplantation can be
detected by using clinical, cytogenetic, or molecular tools. A modification of the polymerase …

Minimal residual disease after bone marrow transplant for chronic myeloid leukaemia detected by the polymerase chain reaction

NCP Cross, L Feng, J Bungey… - Leukemia & …, 1993 - Taylor & Francis
We describe the methodology and application of the polymerase chain reaction to detect
BCR-ABL mRNA as a marker for CML cells. The technique is highly sensitive enabling the …

Detection of minimal residual disease by polymerase chain reaction of bcr/abl transcripts in chronic myelogenous leukaemia following allogeneic bone marrow …

M Lee, I Khouri, R Champlin… - British journal of …, 1992 - Wiley Online Library
The prognostic significance of detecting minimal residual disease by polymerase chain
reaction (PCR) amplification of bcr/abl mRNA transcripts was investigated in 27 bone …

Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a …

K Miyamura, T Tahara, M Tanimoto, Y Morishita… - 1993 - ashpublications.org
We report here the results of polymerase chain reaction (PCR) for bcr-abl transcript and
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …

Frequent detection of BCR-ABL specific mRNA in patients with chronic myeloid leukemia (CML) following allogeneic and syngeneic bone marrow transplantation …

A Gaiger, T Lion, P Kalhs, G Mitterbauer, T Henn… - Leukemia, 1993 - europepmc.org
We performed a two-step polymerase chain reaction (PCR) to detect bcr-abl-specific mRNA
in 440 peripheral blood and/or bone marrow samples of 30 chronic myeloid leukemia (CML) …

Competitive polymerase chain reaction to estimate the number of BCR-ABL transcripts in chronic myeloid leukemia patients after bone marrow transplantation

NC Cross, L Feng, A Chase, J Bungey, TP Hughes… - 1993 - ashpublications.org
We have developed a competitive polymerase chain reaction (PCR) titration assay that
estimates the number of BCR-ABL transcripts in chronic myeloid leukemia patients to …

Detection of minimal residual disease in chronic myeloid leukemia patients after bone marrow transplantation by polymerase chain reaction.

MH Delfau, JP Kerckaert, P Fenaux, JL Lai, JP Jouet… - Leukemia, 1990 - europepmc.org
We used a modification of the polymerase chain reaction (PCR) to amplify the specific bcr-
abl mRNA from 14 patients with chronic myeloid leukemia (CML) who had previously …

Detection of Philadelphia chromosome-positive cells by the polymerase chain reaction following bone marrow transplant for chronic myelogenous leukemia

MS Roth, JH Antin, EL Bingham, D Ginsburg - 1989 - ashpublications.org
Sixteen patients treated by allogeneic bone marrow transplantation (BMT) for chronic
myelogenous leukemia (CML) were evaluated by the polymerase chain reaction (PCR) for …

Persistence of bcr-abl gene expression following bone marrow transplantation for chronic myelogenous leukemia in chronic phase

DS SNYDER, JJ ROSSI, JLIN WANG… - …, 1991 - journals.lww.com
The bcr-abl RNA transcript is the molecular counterpart of the Philadelphia chromosome
and is detectable by an extremely sensitive polymerase chain reaction assay in most …