Efficacy and Safety of Gefitinib Plus Anlotinib for Patients with EGFR Positive Advanced Non-Small-Cell Lung Cancer: A Retrospective Exploratory Study

WX Hu, JC Peng, Y Wang, H Jin… - International Journal of …, 2022 - Taylor & Francis
Objective This study was to investigate the efficacy and safety of gefitinib plus anlotinib for
patients with EGFR positive advanced non-small cell lung cancer (NSCLC) in a first-line …

[HTML][HTML] Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a …

S Watanabe, J Tanaka, T Ota, R Kondo, H Tanaka… - BMC cancer, 2011 - Springer
Background Gefitinib was the first epidermal growth factor receptor-tyrosine kinase inhibitor
(EGFR-TKI) approved for the treatment of advanced non-small cell lung cancer (NSCLC) …

[HTML][HTML] Comparison of gefitinib plus chemotherapy versus gefitinib alone for advanced non-small-cell lung cancer: A meta analysis

M Yi, T He, K Wang, Y Wei - Clinics, 2023 - SciELO Brasil
This study aimed to perform a meta-analysis comparing the efficacy and safety of gefitinib in
combination with chemotherapy versus gefitinib alone in patients with advanced Non-Small …

Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non–small-cell lung cancer and poor performance …

G Goss, D Ferry, R Wierzbicki, SA Laurie… - Journal of Clinical …, 2009 - ascopubs.org
Purpose To compare gefitinib with placebo in chemotherapy naïve patients with advanced
non–small-cell lung cancer (NSCLC) and poor performance status. Patients and Methods …

The combination of EGFR-TKIs and anlotinib as a first-line therapy for EGFR-mutant advanced non-small cell lung cancer: A multicenter, single-arm, phase II clinical …

Z He, J Lin, Y He, J Zhang, D Yang, W Qiu, J Lai… - 2021 - ascopubs.org
9030 Background: Currently, EGFR-TKIs are widely accepted as the standard treatment for
EGFR-mutant advanced non-small-cell lung cancer (NSCLC); however, acquired resistance …

Concurrent use of anlotinib overcomes acquired resistance to EGFR‐TKI in patients with advanced EGFR‐mutant non‐small cell lung cancer

C Zhang, H Cao, Y Cui, S Jin, W Gao… - Thoracic …, 2021 - Wiley Online Library
Background Acquired resistance development is a major challenge in the epidermal growth
factor receptor‐tyrosine kinase inhibitor (EGFR–TKI) treatment of non–small cell lung cancer …

Effect of gefitinib combined with chemotherapy in patients with advanced NSCLC: A retrospective cohort study

L Dai, W Wang, W Li, Y Wu, K Qu - International Journal of General …, 2022 - Taylor & Francis
Background There are currently no methods for the treatment of reversible drug-resistant
EGFR-TKI lung cancer in the clinical setting, and thus, the patients finally return to the …

A phase II trial of gefitinib monotherapy in pretreated patients with advanced non-small cell lung cancer not harboring activating EGFR mutations: implications of …

MK Choi, JY Hong, WJ Chang, MJ Kim, SM Kim… - Cancer chemotherapy …, 2015 - Springer
Purpose Efficacy of gefitinib therapy strongly depends on epidermal growth factor receptor
(EGFR) mutation status in patients with non-small cell lung cancer (NSCLC). However …

Continued gefitinib retreatment beyond progression in patients with advanced non-small cell lung cancer harboring sensitive EGFR mutations

X Jiang, X Li, L Tu, J Cai, M Wei… - Journal of International …, 2020 - journals.sagepub.com
Purpose To evaluate the effectiveness and safety of gefitinib retreatment beyond disease
progression in patients with advanced non-small cell lung cancer (NSCLC) with sensitive …

A multicenter, randomized, double-blind study of gefitinib in combination with anlotinib or placebo in previously untreated patients with EGFR mutation-positive …

L Zhang, W Fang, Y Yang, Q Yu, D Wu, Y Lin, H Zhang… - 2021 - ascopubs.org
TPS9131 Background: Preclinical and clinical evidence has demonstrated that the dual
blockade of the EGFR and VEGF pathways is a viable strategy in the EGFR-mutated …