Genetic reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs)
could offer replenishable cell sources for transplantation therapies. To fulfill their promises …

Over a decade ago, a landmark study that reported derivation of induced Pluripotent Stem
Cells (iPSCs) by reprogramming fibroblasts has transformed stem cell research attracting …

More than a decade ago, a pioneering study reported generation of induced Pluripotent
Stem Cells (iPSCs) by ectopic expression of a cocktail of reprogramming factors in …

Stem cells are classified into embryonic stem cells and adult stem cells. An evolving
alternative to conventional stem cell therapies is induced pluripotent stem cells (iPSCs) …

Introduction The reprogramming of a patient's somatic cells back into induced pluripotent
stem cells (iPSCs) holds significant promise for future autologous cellular therapeutics. The …

To date, all methods to generate induced pluripotent stem cells (iPSCs) require the use of
genetic materials and/or potentially mutagenic molecules. Here we report the generation of …

The concept of reversing the characteristics of differentiated tissues to pluripotency through
reprogramming was introduced over 50 years ago in the first somatic cell nuclear transfer …

Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) can be achieved
by viral-mediated transduction of defined transcription factors. Moving toward the eventual …

We recently demonstrated the chemical reprogramming of human somatic cells to
pluripotent stem cells (hCiPSCs), which provides a robust approach for cell fate …

Reprogramming human adult blood mononuclear cells (MNCs) cells by transient plasmid
expression is becoming increasingly popular as an attractive method for generating induced …