Prevention of postoperative pericardial adhesions with a hyaluronic acid coating solution: Experimental safety and efficacy studies

JD Mitchell, R Lee, GT Hodakowski, K Neya… - The Journal of Thoracic …, 1994 - Elsevier
Postoperative pericardial adhesions complicate reoperative cardiac procedures. Topical
application of solutions containing hyaluronic acid have been shown to reduce adhesions …

Reduction in experimental pericardial adhesions using a hyaluronic acid bioabsorbable membrane

JD Mitchell, R Lee, K Neya… - European journal of …, 1994 - academic.oup.com
Various materials have been suggested for pericardial closure followingcardiac surgery to
limit postoperative adhesion formation. Unfortunately, these devices have caused difficulties …

Prevention of postoperative pericardial adhesions using tissue-protective solutions

JM Seeger, LD Kaelin, EM Staples, Y Yaacobi… - Journal of Surgical …, 1997 - Elsevier
Repeat cardiac surgical procedures are associated with increased technical difficulty and
risk because of the previous formation of dense adhesions between the heart and the …

[HTML][HTML] A novel method to reduce pericardial adhesion: a combination technique with hyaluronic acid biocompatible membrane

Y Naito, T Shin'oka, N Hibino, G Matsumura… - The Journal of thoracic …, 2008 - Elsevier
OBJECTIVE: This study was to evaluate the efficacy of the hyarulonic acid (HA)
bioabsorbable membrane combined use with both expanded-polytetrafluoroethylene …

The effects of barrier materials on reduction of pericardial adhesion formation in rabbits: a comparative study of a hyaluronan-based solution and a temperature …

JH Hong, JW Choe, GY Kwon, DY Cho… - Journal of Surgical …, 2011 - Elsevier
OBJECTIVE: This study was performed to examine the efficacy and safety of a hyaluronan
solution (Guardix-SL) and a temperature sensitive poloxamer solution/gel material (Guardix …

Postoperative pericardial adhesion prevention using Carbylan-SX in a rabbit model

RC Connors, JJ Muir, Y Liu, GR Reiss… - Journal of Surgical …, 2007 - Elsevier
INTRODUCTION: The presence of dense adhesions within the pericardial space
complicates reoperative cardiac surgery. Prior attempts to reduce adhesion formation after …

Prevention of postoperative pericardial adhesions with hydrophilic polymer solutions

DA Duncan, Y Yaacobi, EP Goldberg, M Mines… - Journal of Surgical …, 1988 - Elsevier
Pericardial adhesions subject patients requiring cardiac reoperation to potential injuries of
the heart, great vessels, and extracardiac grafts during resternotomy. We evaluated …

Prevention of pericardial adhesions with NO carboxymethylchitosan in the rabbit model

TJ Krause, G Zazanis, P Malatesta… - Journal of Investigative …, 2001 - Taylor & Francis
The presence of mediastinal adhesions significantly increases the morbidity and mortality of
reoperative cardiac surgical procedures. Previous investigations have reported on the …

Reducing the incidence and severity of pericardial adhesions with a sprayable polymeric matrix

WF Konertz, M Kostelka, FW Mohr, R Hetzer… - The Annals of thoracic …, 2003 - Elsevier
PURPOSE: This study was undertaken to evaluate the antiadhesive properties of a
polymeric agent in infants undergoing staged surgical correction of congenital heart …

Effect of topical N-acetylcysteine in the prevention of postoperative pericardial adhesion formation in a rabbit model

N Colak, Y Nazli, MF Alpay, ON Aksoy, IO Akkaya… - Cardiovascular …, 2013 - Elsevier
Abstract Background N-acetylcysteine (NAC), a precursor of reduced glutathione, has been
in clinical use primarily as a mucolytic. In addition, NAC is well known for their free radical …