[HTML][HTML] Protective effects of dihydroquercetin on an APAP-induced acute liver injury mouse model

X Chen, J Huang, Z Hu, Q Zhang, X Li… - International Journal of …, 2017 - ncbi.nlm.nih.gov
Dihydroquercetin (DHQ) is a flavonoid in the Chinese traditional herbal medicine Ramulus
Euonymi, which has anti-inflammatory, antioxidant and anticancer bioactivity. In the present …

Dihydroquercetin ameliorated acetaminophen-induced hepatic cytotoxicity via activating JAK2/STAT3 pathway and autophagy

W Zai, W Chen, J Luan, J Fan, X Zhang, Z Wu… - Applied microbiology …, 2018 - Springer
Acetaminophen (APAP) overdose is currently the leading cause of acute liver disease, but
therapeutic treatment strategies are commonly limited. Although dihydroquercetin (DHQ) is …

The protective effect of aspirin eugenol ester on paraquat-induced acute liver injury rats

ZD Zhang, YJ Yang, XW Liu, Z Qin, SH Li… - Frontiers in Medicine, 2020 - frontiersin.org
Aspirin eugenol ester (AEE) possesses anti-inflammatory and anti-oxidative effects. The
study was conducted to evaluate the protective effect of AEE on paraquat-induced acute …

Dihydroquercetin (DHQ) ameliorated concanavalin A-induced mouse experimental fulminant hepatitis and enhanced HO-1 expression through MAPK/Nrf2 antioxidant …

M Zhao, J Chen, P Zhu, M Fujino, T Takahara… - International …, 2015 - Elsevier
Autoimmune hepatitis represents a ubiquitous human health problem and has a poor
prognosis. Dihydroquercetin (DHQ), a well-known antioxidant, significantly inhibits fulminant …

ERK/NF-kB/COX-2 signaling pathway plays a key role in curcumin protection against acetaminophen-induced liver injury

AH Chou, HC Lee, CC Liao, HP Yu, FC Liu - Life, 2023 - mdpi.com
Recent experimental studies have highlighted the beneficial effects of curcumin on liver
injury induced by acetaminophen (APAP). However, the specific molecular mechanisms …

Amygdalin protects against acetaminophen-induced acute liver failure by reducing inflammatory response and inhibiting hepatocyte death

C Zhang, J Lin, C Zhen, F Wang, X Sun, X Kong… - Biochemical and …, 2022 - Elsevier
Amygdalin is a natural compound from Bitter Apricot Seed which is reported to have anti-
inflammatory activity. Acetaminophen (APAP) resulted in drug-induced liver injury is the …

Protective effect of dihydrokaempferol on acetaminophen-induced liver injury by activating the SIRT1 pathway

J Zhang, C Hu, X Li, L Liang, M Zhang… - The American Journal …, 2021 - World Scientific
Acetaminophen (APAP) overdose is the leading cause of acute liver failure (ALF) in the
Western world, with limited treatment opportunities. 3, 5, 7, 4′-Tetrahydroxyflavanone …

Astaxanthin pretreatment attenuates acetaminophen-induced liver injury in mice

J Zhang, S Zhang, J Bi, J Gu, Y Deng, C Liu - International …, 2017 - Elsevier
Background Acetaminophen (APAP) is a conventional drug widely used in the clinic
because of its antipyretic-analgesic effects. However, accidental or intentional APAP …

Hesperetin attenuated acetaminophen-induced hepatotoxicity by inhibiting hepatocyte necrosis and apoptosis, oxidative stress and inflammatory response via …

J Wan, G Kuang, L Zhang, R Jiang, Y Chen… - International …, 2020 - Elsevier
Acetaminophen (APAP) is a common antipyretic and analgesic drug, but its overdose can
induce acute liver failure with lack of effective therapies. Hesperetin, a dihydrogen flavonoid …

Protective effect of quercetin against macrophage-mediated hepatocyte injury via anti-inflammation, anti-apoptosis and inhibition of ferroptosis

Y Hou, C Chen, Z Li, J Wu, S Lyu, D Guo, Y Liu… - …, 2024 - Taylor & Francis
Yinchenhao Decoction (YCHD) is a classic prescription in traditional Chinese medicine
(TCM). It appears to play an important role in anti-inflammation and autoimmunity protection …