In this review, we explored the therapeutic potential of oleuropein (OLE) and hydroxytyrosol
(HT) in the treatment of neuroblastoma (NB). NB is an extracranial tumour that …

Neuroblastoma (NB) is the most common extra-cranial solid tumor of pediatric age. The
prognosis for high-risk NB patients remains poor, and new treatment strategies are …

Oxidative stress is involved in many of the stages of tumorigenesis, and the administration of
exogenous antioxidants seems to modulate them. Thus, it has been described that …

Most therapies do not discriminate between normal and cancerous cells, leading to toxicity
and unwanted side effects. In this sense, the oleuropein, minor component of extra virgin …

Compounds of natural origin may constitute an interesting tool for the treatment of
neuroblastoma, the most prevalent extracranial solid tumor in children. PRES is a …

Brain tumorigenesis has been associated not only with oxidative stress, but also with a
reduced response of non-enzyme and enzyme antioxidant defense systems. In fact, the …

Background Triterpene alcohols and acids are multifunctional compounds widely distributed
throughout the plant kingdom that exhibit a variety of beneficial health properties, being …

The effects of Olea europaea leaf extract (OLE) phenolics, including oleuropein (OL),
hydroxytyrosol (HT), tyrosol (TYR), and rutin against glioblastoma (GB), independently and …

Glioblastoma (GBM) is the most common primary tumor of the central nervous system.
Current treatments available for GBM entails surgical resection followed by temozolomide …

The fact that the Mediterranean diet could represent a source of natural compounds with
cancer-preventive and therapeutic activity has been the object of great interest, especially …