Anomalous transport in the crowded world of biological cells

F Höfling, T Franosch - Reports on Progress in Physics, 2013 - iopscience.iop.org
A ubiquitous observation in cell biology is that the diffusive motion of macromolecules and
organelles is anomalous, and a description simply based on the conventional diffusion …

Elucidating the origin of anomalous diffusion in crowded fluids

J Szymanski, M Weiss - Physical review letters, 2009 - APS
Anomalous diffusion in crowded fluids, eg, in the cytoplasm of living cells, is a frequent
phenomenon. So far, however, the associated stochastic process, ie, the propagator of the …

Fractional Brownian motion in crowded fluids

D Ernst, M Hellmann, J Köhler, M Weiss - Soft Matter, 2012 - pubs.rsc.org
Diffusion in crowded fluids, eg in the cytoplasm of living cells, has frequently been reported
to show anomalous characteristics (so-called 'subdiffusion'). Several random walk models …

Crowding effects on diffusion in solutions and cells

JA Dix, AS Verkman - Annu. Rev. Biophys., 2008 - annualreviews.org
We review the effects of molecular crowding on solute diffusion in solution and in cellular
aqueous compartments and membranes. Anomalous diffusion, in which mean squared …

Anomalous diffusion of single particles in cytoplasm

BM Regner, D Vučinić, C Domnisoru, TM Bartol… - Biophysical journal, 2013 - cell.com
The crowded intracellular environment poses a formidable challenge to experimental and
theoretical analyses of intracellular transport mechanisms. Our measurements of single …

Unexpected crossovers in correlated random-diffusivity processes

W Wang, F Seno, IM Sokolov, AV Chechkin… - New Journal of …, 2020 - iopscience.iop.org
The passive and active motion of micron-sized tracer particles in crowded liquids and inside
living biological cells is ubiquitously characterised by'viscoelastic'anomalous diffusion, in …

Anomalous subdiffusion is a measure for cytoplasmic crowding in living cells

M Weiss, M Elsner, F Kartberg, T Nilsson - Biophysical journal, 2004 - cell.com
Macromolecular crowding dramatically affects cellular processes such as protein folding and
assembly, regulation of metabolic pathways, and condensation of DNA. Despite increased …

A model of non-Gaussian diffusion in heterogeneous media

Y Lanoiselée, DS Grebenkov - Journal of Physics A …, 2018 - iopscience.iop.org
Recent progress in single-particle tracking has shown evidence of the non-Gaussian
distribution of displacements in living cells, both near the cellular membrane and inside the …

Identifying heterogeneous diffusion states in the cytoplasm by a hidden Markov model

J Janczura, M Balcerek, K Burnecki, A Sabri… - New Journal of …, 2021 - iopscience.iop.org
Diffusion of nanoparticles in the cytoplasm of live cells has frequently been reported to
exhibit an anomalous and even heterogeneous character, ie particles seem to switch gears …

Anomalous subdiffusion in living cells: Bridging the gap between experiments and realistic models through collaborative challenges

M Woringer, I Izeddin, C Favard, H Berry - Frontiers in Physics, 2020 - frontiersin.org
The life of a cell is governed by highly dynamical microscopic processes. Two notable
examples are the diffusion of membrane receptors and the kinetics of transcription factors …