Albumin nano-encapsulation of piceatannol enhances its anticancer potential in colon cancer via down regulation of nuclear p65 and HIF-1α

A AA Aljabali, H A. Bakshi, F L. Hakkim, YA Haggag… - Cancers, 2020 - mdpi.com
Piceatannol (PIC) is known to have anticancer activity, which has been attributed to its ability
to block the proliferation of cancer cells via suppression of the NF-kB signaling pathway …

Piceatannol-loaded emulsomes exhibit enhanced cytostatic and apoptotic activities in colon cancer cells

NA Alhakamy, SM Badr-Eldin, OAA Ahmed, HZ Asfour… - Antioxidants, 2020 - mdpi.com
Piceatannol (PIC), a naturally occurring polyphenolic stilbene, has pleiotropic
pharmacological activities. It has reported cytotoxic activities against different cancer cells. In …

The effect of encapsulated apigenin nanoparticles on HePG-2 cells through regulation of P53

MM Mabrouk Zayed, HA Sahyon, NAN Hanafy… - Pharmaceutics, 2022 - mdpi.com
Apigenin (Ap) is one of the most important natural flavonoids that has potent anticancer
activity. This study was designed, for the first time, to load Ap into chitosan to improve its …

Pectin-tannic acid nano-complexes promote the delivery and bioactivity of drugs in pancreatic cancer cells

SS Chauhan, AB Shetty, E Hatami, P Chowdhury… - Pharmaceutics, 2020 - mdpi.com
Pancreatic cancer (PanCa) is a lethal disease. Conventional chemotherapies for PanCa
offer severe systemic toxicities. Thus, the development of a successful nanomedicine-based …

Polyphenol-based nanoparticles: a promising frontier for enhanced colorectal cancer treatment

H Wahnou, B Liagre, V Sol, H El Attar, R Attar… - Cancers, 2023 - mdpi.com
Simple Summary Conventional therapies for the treatment of colorectal cancer induce
several side effects that impact the effectiveness of current therapies as well as the quality of …

Poly (ferulic acid) with an anticancer effect as a drug nanocarrier for enhanced colon cancer therapy

Y Zheng, X You, S Guan, J Huang… - Advanced Functional …, 2019 - Wiley Online Library
As colorectal cancer is the fourth leading cause of cancer‐related death worldwide,
colorectal cancer therapy requires new strategies for improved therapeutic effects. Recently …

Apigenin loaded nanoparticle delayed development of hepatocellular carcinoma in rats

S Bhattacharya, L Mondal, B Mukherjee, L Dutta… - … , Biology and Medicine, 2018 - Elsevier
Hepatocellular carcinoma (HCC) is one of the major causes of cancer related death globally.
Apigenin, a dietary flavonoid, possesses anti-tumor activity against HCC cells in-vitro …

Nanoencapsulated betulinic acid analogue distinctively improves colorectal carcinoma in vitro and in vivo

D Dutta, B Paul, B Mukherjee, L Mondal, S Sen… - Scientific reports, 2019 - nature.com
Betulinic acid, a plant secondary metabolite, has gained significant attention due to its
antiproliferative activity over a range of cancer cells. A promising betulinic acid analogue …

Enhanced anti-cancer effect of artemisinin-and curcumin-loaded niosomal nanoparticles against human colon cancer cells

A Firouzi Amandi, E Jokar, M Eslami, M Dadashpour… - Medical Oncology, 2023 - Springer
Colorectal cancer (CRC) is the third broadly identified cancer in the world. The
ineffectiveness of colorectal cancer treatment is redundantly reported. Natural bioactive …

Nanoencapsulation of polyphenols for protective effect against colon–rectal cancer

IS Santos, BM Ponte, P Boonme, AM Silva… - Biotechnology …, 2013 - Elsevier
The human population at large is exposed to many critical factors (eg bad food habits,
chemical substances, and stress) leading to the development of serious diseases. Colon or …