On the biological significance of DNA methylation

W Doerfler - Biochemistry (Moscow), 2005 - Springer
This chapter presents a personal account of the work on DNA methylation in viral and
mammalian systems performed in the author's laboratory in the course of the past thirty …

De novo methylation, long-term promoter silencing, methylation patterns in the human genome, and consequences of foreign DNA insertion

W Doerfler - DNA Methylation: Basic Mechanisms, 2006 - Springer
This chapter presents a personal account of the work on DNA methylation in viral and
mammalian systems performed in the author's laboratory in the course of the past 30 years …

Enzymatic DNA methylation is an epigenetic control for genetic functions of the cell

BF Vanyushin - Biochemistry (Moscow), 2005 - Springer
In eukaryotic cells nuclear DNA is subjected to enzymatic methylation resulting in formation
of 5-methylcytosine residues mainly in CG and CNG sequences. In plants and animals, this …

DNA methylation and epigenetics

BF Vanyushin - Russian Journal of Genetics, 2006 - Springer
In eukaryotic cells, nuclear DNA is subject to enzymatic methylation with the formation of 5-
methylcytosine residues, mostly within the CG and CNG sequences. In plants and animals …

The controversial denouement of vertebrate DNA methylation research

M Ehrlich - Biochemistry (Moscow), 2005 - Springer
The study of the biological role of DNA methylation in vertebrates has involved considerable
controversy. Research in this area has proceeded well despite the complexity of the subject …

DNA methyltransferases and structural-functional specificity of eukaryotic DNA modification

YI Buryanov, TV Shevchuk - Biochemistry (Moscow), 2005 - Springer
Abstract Properties of the main families of mammalian, plant, and fungal DNA
methyltransferases are considered. Structural-functional specificity of eukaryotic genome …

The language of methylation in genomics of eukaryotes

P Volpe - Biochemistry (Moscow), 2005 - Springer
Background studies have shown that 6-methylaminopurine (m 6 A) and 5-methylcytosine (m
5 C), detected in DNA, are products of its post-synthetic modification. At variance with …

DNA methylation and its possible biological roles

A Razin, J Friedman - Progress in nucleic acid research and molecular …, 1981 - Elsevier
Publisher Summary The chapter discusses on the DNA methylation and its possible
biological roles. The pattern of DNA methylation is species-specific. In the DNA of some …

DNA demethylation and carcinogenesis

NP Kisseljova, FL Kisseljov - Biochemistry (Moscow), 2005 - Springer
DNA methylation plays an important role in the establishment and maintenance of the
program of gene expression. Tumor cells are characterized by a paradoxical alteration of …

DNA methylation and epigenotypes

R Holliday - Biochemistry (Moscow), 2005 - Springer
The science of epigenetics is the study of all those mechanisms that control the unfolding of
the genetic program for development and determine the phenotypes of differentiated cells …