Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5

SN Kłodzińska, D Pletzer, N Rahanjam, T Rades… - … , Biology and Medicine, 2019 - Elsevier
Anti-biofilm peptides are a subset of antimicrobial peptides and represent promising broad-
spectrum agents for the treatment of bacterial biofilms, though some display host toxicity in …

Antimicrobial d-Peptide Hydrogels

Z Guo, Y Wang, T Tan, Y Ji, J Hu… - … Biomaterials Science & …, 2021 - ACS Publications
Biofilms are widely involved in human lives, such as in medical infection, environmental
remediation, and industrial processes. However, the control of the biofilm has still been a …

[HTML][HTML] Using anti-biofilm peptides to treat antibiotic-resistant bacterial infections

C de la Fuente-Núñez… - Postdoc journal: a journal …, 2015 - ncbi.nlm.nih.gov
Host defense (antimicrobial) peptides (HDPs) are produced by virtually all organisms and
have an important role in protection against microbial infections. Some naturally occurring …

Design and assessment of anti-biofilm peptides: steps toward clinical application

M Dostert, CR Belanger, REW Hancock - Journal of innate immunity, 2019 - karger.com
Highly antibiotic resistant, microbial communities, referred to as biofilms, cause various life-
threatening infections in humans. At least two-thirds of all clinical infections are biofilm …

[HTML][HTML] Critical assessment of methods to quantify biofilm growth and evaluate antibiofilm activity of host defence peptides

EF Haney, MJ Trimble, JT Cheng, Q Vallé… - Biomolecules, 2018 - mdpi.com
Biofilms are multicellular communities of bacteria that can adhere to virtually any surface.
Bacterial biofilms are clinically relevant, as they are responsible for up to two-thirds of …

[HTML][HTML] Anti-Biofilm Effects of Rationally Designed Peptides against Planktonic Cells and Pre-Formed Biofilm of Pseudomonas aeruginosa

YM Kim, H Son, SC Park, JK Lee, MK Jang, JR Lee - Antibiotics, 2023 - mdpi.com
Biofilms are resistant to antibiotics and are a major source of persistent and recurring
infections by clinically important pathogens. Drugs used for biofilm-associated infections are …

Inhibition of bacterial biofilm formation and swarming motility by a small synthetic cationic peptide

C De La Fuente-Núñez, V Korolik, M Bains… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Biofilms cause up to 80% of infections and are difficult to treat due to their substantial
multidrug resistance compared to their planktonic counterparts. Based on the observation …

Synthetic peptides that form nanostructured micelles have potent antibiotic and antibiofilm activity against polymicrobial infections

S Chou, H Guo, FG Zingl, S Zhang… - Proceedings of the …, 2023 - National Acad Sciences
The emergence of multidrug-resistant bacterial pathogens is a growing threat to global
public health. Here, we report the development and characterization of a panel of nine …

[HTML][HTML] Biofilms: Novel strategies based on antimicrobial peptides

E Galdiero, L Lombardi, A Falanga, G Libralato… - Pharmaceutics, 2019 - mdpi.com
The problem of drug resistance is very worrying and ever increasing. Resistance is due not
only to the reckless use of antibiotics but also to the fact that pathogens are able to adapt to …

Antibiofilm peptides: potential as broad-spectrum agents

D Pletzer, REW Hancock - Journal of bacteriology, 2016 - Am Soc Microbiol
The treatment of bacterial diseases is facing twin threats, with increasing bacterial antibiotic
resistance and relatively few novel compounds or strategies under development or entering …