RBBP4 is a nuclear WD40 motif-containing protein widely implicated in various cancers and
a putative drug target. It interacts with multiple proteins within diverse complexes such as …

Abstract RBBP4 and RBBP7 (RBBP4/7) are highly homologous nuclear WD40 motif
containing proteins widely implicated in various cancers and are valuable drug targets. They …

Regulators of the tumour suppressor protein, p53 are promising anti-cancer drug
candidates. The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, has …

Retinoblastoma-binding protein (RBBP) family is a class of proteins that can interact with
tumor suppressor retinoblastoma protein (pRb). RBBP4 and RBBP7 are the only pair of …

The retinoblastoma binding protein 6 (RBBP6) proteins (also called P-53 Associated Cell
Testis Derived (PACT)) are highly upregulated in esophageal cancer and enhance the …

As a step towards better integrating protein three-dimensional (3D) structural information in
cancer systems biology, the Northeast Structural Genomics Consortium (NESG)(www. nesg …

RBBP6 is a 250 kDa eukaryotic protein known to be a negative regulator of p53 and
essential for embryonic development. Furthermore, RBBP6 is a critical element in …

The retinoblastoma (RB) tumor suppressor protein controls cell cycle progression by
regulating the activity of the transcription factor E2F, which activates genes essential for DNA …

Hepatocellular carcinoma (HCC) is one of the most common malignancy tumors with
insidious onset, rapid development and metastasis, and poor prognosis. Therefore, it is …

Simple Summary Rb1 is a regulator of cell cycle progression and genomic stability. This
review focuses on post-translational modifications, their effect on Rb1 interactors, and their …