Safety and efficacy of angiotensin-converting enzyme inhibitors in symptomatic severe aortic stenosis: symptomatic cardiac obstruction–pilot study of enalapril in aortic …

A Chockalingam, S Venkatesan, T Subramaniam… - American heart …, 2004 - Elsevier
BACKGROUND: Animal models have demonstrated a benefit of angiotensin-converting
enzyme inhibitors (ACEI) in experimental aortic stenosis (AS), and intravenous nitroprusside …

Short-term hemodynamic effect of angiotensin-converting enzyme inhibition in patients with severe aortic stenosis: a placebo-controlled, randomized study

M Dalsgaard, K Iversen, J Kjaergaard, P Grande… - American Heart …, 2014 - Elsevier
Background In patients with severe aortic stenosis (AS), treatment with angiotensin-
converting enzyme inhibitors has previously been considered contraindicated. However …

Effects of angiotensin converting enzyme inhibitors in hypertensive patients with aortic valve stenosis: a drug withdrawal study

J Jimenez-Candil, J Bermejo, R Yotti, C Cortina… - Heart, 2005 - heart.bmj.com
Objective: To determine the effects of angiotensin converting enzyme (ACE) inhibitors in
hypertensive patients with aortic valve stenosis (AS). Design: Observational, drug …

Hemodynamic effects of the angiotensin-converting enzyme inhibitor, ramipril, in patients with mild to moderate aortic stenosis and preserved left ventricular function

KD O'Brien, XQ Zhao, DM Shavelle… - Journal of …, 2004 - journals.sagepub.com
Background Angiotensin-converting enzyme (ACE) inhibitor use is presumed to be
contraindicated in patients with aortic stenosis (AS). We determined the hemodynamic …

ACE inhibition in aortic stenosis: dangerous medicine or golden opportunity?

HC Routledge, JN Townend - Journal of human hypertension, 2001 - nature.com
Conventionally angiotensin-converting enzyme (ACE) inhibitors are contraindicated in
patients with aortic stenosis. Abundant evidence is now available showing that angiotensin II …

A prospective, double-blind, randomized controlled trial of the angiotensin-converting enzyme inhibitor Ramipril In Aortic Stenosis (RIAS trial)

S Bull, M Loudon, JM Francis, J Joseph… - European Heart …, 2015 - academic.oup.com
Aims Angiotensin-converting enzyme (ACE) inhibitors improve left ventricular (LV)
remodelling and outcome in heart failure and hypertensive heart disease. They may be …

Impact of renin-angiotensin system blockade therapy on outcome in aortic stenosis

MA Nadir, L Wei, DHJ Elder, R Libianto, TK Lim… - Journal of the American …, 2011 - jacc.org
Objectives: The purpose of this study was to investigate the impact of renin-angiotensin
system blockade therapy on outcomes in aortic stenosis (AS). Background: Angiotensin …

Impact of hypertension and renin–angiotensin system inhibitors in aortic stenosis

R Capoulade, MA Clavel, P Mathieu… - European journal of …, 2013 - Wiley Online Library
Background Experimental studies revealed that renin–angiotensin system (RAS) could play
a crucial role in the pathophysiology of aortic stenosis (AS). The objectives of this study were …

Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending …

EO Weinberg, FJ Schoen, D George, Y Kagaya… - Circulation, 1994 - Am Heart Assoc
BACKGROUND We tested the hypotheses that long-term administration of the angiotensin-
converting enzyme (ACE) inhibitor fosinopril will regress hypertrophy, modify the transition to …

Clinical outcome with enalapril in symptomatic chronic heart failure; a dose comparison

P Poole-Wilson, J Cleland, W Hubbard… - European heart …, 1998 - research.ed.ac.uk
Background Angiotensin converting-enzyme (ACE) inhibitors used for the treatment of heart
failure relieve symptoms, increase exercise performance, reduce hospital admissions and …