Protective effect of Epicatechin on APAP-induced acute liver injury of mice through anti-inflammation and apoptosis inhibition

H Wu, Y Xie, Y Xu, Z Hu, X Wan, H Huang… - Natural product …, 2020 - Taylor & Francis
Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.) Sieb, and
possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and …

[HTML][HTML] Hepatoprotective Effects of (−) Epicatechin in CCl4-Induced Toxicity Model Are Mediated via Modulation of Oxidative Stress Markers in Rats

KB Alkinani, EMM Ali, TM Al-Shaikh… - Evidence-based …, 2021 - ncbi.nlm.nih.gov
Objective (−) Epicatechin (EP) is a naturally occurring antioxidant flavonoid found in some
green plants. The current study was designed to evaluate the potential role of antioxidant …

[HTML][HTML] Protective effects of dihydroquercetin on an APAP-induced acute liver injury mouse model

X Chen, J Huang, Z Hu, Q Zhang, X Li… - International Journal of …, 2017 - ncbi.nlm.nih.gov
Dihydroquercetin (DHQ) is a flavonoid in the Chinese traditional herbal medicine Ramulus
Euonymi, which has anti-inflammatory, antioxidant and anticancer bioactivity. In the present …

Hepatoprotective effects of an active part from Artemisia sacrorum Ledeb. against acetaminophen-induced toxicity in mice

HD Yuan, GZ Jin, GC Piao - Journal of ethnopharmacology, 2010 - Elsevier
AIMS OF STUDY: Although Artemisia sacrorum Ledeb.(Compositae) has long been used as
one kind of oriental folk medicine to treat some liver diseases, the underlying mechanism (s) …

[HTML][HTML] Hepatoprotective effects of Elaeagnus latifolia fruit extract against acetaminophen-induced hepatotoxicity in mice: Mechanistic insights

N Munkong, K Ruxsanawet, V Ariyabukalakorn… - Journal of Functional …, 2024 - Elsevier
Elaeagnus latifolia fruit extract (EE) has been reported to contain antioxidant and anti-
inflammatory phytochemicals. The present study aimed to examine the anti-hepatotoxic …

[HTML][HTML] Escin protects against acetaminophen-induced liver injury in mice via attenuating inflammatory response and inhibiting ERK signaling pathway

HC Lee, HP Yu, CC Liao, AH Chou… - American Journal of …, 2019 - ncbi.nlm.nih.gov
Acetaminophen (APAP) overdose may lead to the formation of oxidative stress, hepatocyte
apoptosis and necrosis, and, eventually result in acute liver failure. Escin, a major extracted …

[HTML][HTML] Protective effects of an ethanol extract of Angelica keiskei against acetaminophen-induced hepatotoxicity in HepG2 and HepaRG cells

YH Choi, HS Lee, CK Chung, EJ Kim… - Nutrition Research and …, 2017 - ncbi.nlm.nih.gov
RESULTS AK-Ex, when administered prior to AAP, increased cell growth and decreased
leakage of LDH in a dose-dependent manner in HepG2 and HepaRG cells against AAP …

Chrysanthemi Flos extract alleviated acetaminophen-induced rat liver injury via inhibiting oxidative stress and apoptosis based on network pharmacology analysis

Y Zhou, C Wang, J Kou, M Wang, X Rong… - Pharmaceutical …, 2021 - Taylor & Francis
Context Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury.
Bianliang ziyu, a variety of Chrysanthemum morifolium Ramat.(Asteraceae), has potential …

[HTML][HTML] Preliminary study on hepatoprotective effect and mechanism of (-)-epigallocatechin-3-gallate against acetaminophen-induced liver injury in rats

Y Lin, J Huang, T Gao, Y Wu, D Huang… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Antipyretic acetaminophen (APAP) is a commonly used drug that generally associates with
liver injury.(-)-Epigallocatechin-3-gallate (EGCG), an active polyphenol extracted from green …

The Essential Oils and Eucalyptol From Artemisia vulgaris L. Prevent Acetaminophen-Induced Liver Injury by Activating Nrf2–Keap1 and Enhancing APAP Clearance …

Z Jiang, X Guo, K Zhang, G Sekaran, B Cao… - Frontiers in …, 2019 - frontiersin.org
Artemisia has long been used in traditional medicine and as a food source for different
functions in eastern Asia. Artemisia vulgaris L.(AV) is a species of the genus Artemisia …