Historically, ROS have been considered toxic molecules, especially when their intracellular
concentration reaches high values. However, physiological levels of ROS support crucial …

Reactive oxygen species (ROS) have emerged as regulators of key processes supporting
neuronal growth, function, and plasticity across lifespan. At normal physiological levels, ROS …

Aberrant or elevated levels of reactive oxygen species (ROS) can mediate deleterious
cellular effects, including neuronal toxicity and degeneration observed in the etiology of a …

Reactive oxygen species (ROS) are important regulators of intracellular signaling. We
examined the expression of ROS during rat brain development and explored their role in …

Reactive oxygen species (ROS) are critical for maintaining cellular homeostasis and
function when produced in physiological ranges. Important sources of cellular ROS include …

Reactive oxygen species (ROS) have long been studied as destructive agents in the context
of nervous system ageing, disease and degeneration. Their roles as signalling molecules …

A population of embryonic rat cortical cells cultured in the presence of FGF2 and having
neuronal morphology expressed higher levels of reactive oxygen species (ROS) than did …

Methods for growing primary neuronal cultures rely on the inclusion of antioxidants in the
culture medium, but no studies have determined precisely if or when antioxidants are …

Hypoxia-Induced Lipid Peroxidation in the Brain During Postnatal Ontogenesis Page 1
PHYSIOLOGICAL RESEARCH • ISSN 0862-8408(print) • ISSN 1802-9973(online) © 2012 …

The generation of abnormally high levels of reactive oxygen species (ROS) is linked to
cellular dysfunction, including neuronal toxicity and neurodegeneration. However …