Are we any closer to beating the biofilm: novel methods of biofilm control

G Ramage, S Culshaw, B Jones… - Current opinion in …, 2010 - journals.lww.com
Biofilms are inherently difficult to treat, and mechanical disruption is the mainstay of clinical
management. With scientific progress in molecular microbiology, there is an abundance of …

Biofilms: Survival and defense strategy for pathogens

A Kumar, A Alam, M Rani, NZ Ehtesham… - International Journal of …, 2017 - Elsevier
Studies on biofilm related infections are gaining prominence owing to their involvement in
majority of clinical infections. Biofilm, considered as a generic mechanism for survival used …

Eradicating biofilm infections: an update on current and prospective approaches

RAG da Silva, I Afonina, KA Kline - Current Opinion in Microbiology, 2021 - Elsevier
Highlights•Biofilm infections are heterogenous, persistent and recalcitrant.•The rise of
antibiotic resistance necessitates new therapeutic strategies to eradicate biofilms.•The …

[HTML][HTML] Targeting biofilms therapy: current research strategies and development hurdles

Y Jiang, M Geng, L Bai - Microorganisms, 2020 - mdpi.com
Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …

[HTML][HTML] How well are we translating biofilm research from bench-side to bedside?

KP Rumbaugh - Biofilm, 2020 - Elsevier
Biofilms are responsible for more than 80% of all chronic infections and represent an
enormous medical challenge. In order to meet this challenge, translation research on anti …

Novel approaches to combat bacterial biofilms

C Beloin, S Renard, JM Ghigo, D Lebeaux - Current opinion in …, 2014 - Elsevier
Highlights•Currently used antibiotics were developed to target planktonic bacteria.•Recent
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …

Current and emergent control strategies for medical biofilms

MSA Khan, I Ahmad, M Sajid, SS Cameotra - Antibiofilm Agents: From …, 2014 - Springer
In nature, microorganisms prefer to live in structured microbial communities rather than as
free-floating planktonic cells. These dynamic microbial communities are termed biofilms, in …

[HTML][HTML] Strategies for combating antibiotic resistance in bacterial biofilms

KE Grooters, JC Ku, DM Richter, MJ Krinock… - Frontiers in Cellular …, 2024 - frontiersin.org
Biofilms, which are complexes of microorganisms that adhere to surfaces and secrete
protective extracellular matrices, wield substantial influence across diverse domains such as …

New frontiers for anti-biofilm drug development

SM Ribeiro, MR Felício, EV Boas, S Gonçalves… - Pharmacology & …, 2016 - Elsevier
Pathogenic microbial biofilm, a consortium of microbial cells protected by a self-produced
polymer matrix, is considered a worldwide challenge due to the inherent antibiotic …

Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era

M Kostakioti, M Hadjifrangiskou… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Biofilm formation constitutes an alternative lifestyle in which microorganisms adopt a
multicellular behavior that facilitates and/or prolongs survival in diverse environmental …