Are we any closer to beating the biofilm: novel methods of biofilm control
Biofilms are inherently difficult to treat, and mechanical disruption is the mainstay of clinical
management. With scientific progress in molecular microbiology, there is an abundance of …
management. With scientific progress in molecular microbiology, there is an abundance of …
Biofilms: Survival and defense strategy for pathogens
A Kumar, A Alam, M Rani, NZ Ehtesham… - International Journal of …, 2017 - Elsevier
Studies on biofilm related infections are gaining prominence owing to their involvement in
majority of clinical infections. Biofilm, considered as a generic mechanism for survival used …
majority of clinical infections. Biofilm, considered as a generic mechanism for survival used …
Eradicating biofilm infections: an update on current and prospective approaches
Highlights•Biofilm infections are heterogenous, persistent and recalcitrant.•The rise of
antibiotic resistance necessitates new therapeutic strategies to eradicate biofilms.•The …
antibiotic resistance necessitates new therapeutic strategies to eradicate biofilms.•The …
[HTML][HTML] Targeting biofilms therapy: current research strategies and development hurdles
Y Jiang, M Geng, L Bai - Microorganisms, 2020 - mdpi.com
Biofilms are aggregate of microorganisms in which cells are frequently embedded within a
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …
self-produced matrix of extracellular polymeric substance (EPS) and adhere to each other …
[HTML][HTML] How well are we translating biofilm research from bench-side to bedside?
KP Rumbaugh - Biofilm, 2020 - Elsevier
Biofilms are responsible for more than 80% of all chronic infections and represent an
enormous medical challenge. In order to meet this challenge, translation research on anti …
enormous medical challenge. In order to meet this challenge, translation research on anti …
Novel approaches to combat bacterial biofilms
Highlights•Currently used antibiotics were developed to target planktonic bacteria.•Recent
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …
discoveries on biofilm properties led to promising anti-biofilm strategies.•Biofilm inhibition …
Current and emergent control strategies for medical biofilms
In nature, microorganisms prefer to live in structured microbial communities rather than as
free-floating planktonic cells. These dynamic microbial communities are termed biofilms, in …
free-floating planktonic cells. These dynamic microbial communities are termed biofilms, in …
[HTML][HTML] Strategies for combating antibiotic resistance in bacterial biofilms
KE Grooters, JC Ku, DM Richter, MJ Krinock… - Frontiers in Cellular …, 2024 - frontiersin.org
Biofilms, which are complexes of microorganisms that adhere to surfaces and secrete
protective extracellular matrices, wield substantial influence across diverse domains such as …
protective extracellular matrices, wield substantial influence across diverse domains such as …
New frontiers for anti-biofilm drug development
SM Ribeiro, MR Felício, EV Boas, S Gonçalves… - Pharmacology & …, 2016 - Elsevier
Pathogenic microbial biofilm, a consortium of microbial cells protected by a self-produced
polymer matrix, is considered a worldwide challenge due to the inherent antibiotic …
polymer matrix, is considered a worldwide challenge due to the inherent antibiotic …
Bacterial biofilms: development, dispersal, and therapeutic strategies in the dawn of the postantibiotic era
M Kostakioti, M Hadjifrangiskou… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Biofilm formation constitutes an alternative lifestyle in which microorganisms adopt a
multicellular behavior that facilitates and/or prolongs survival in diverse environmental …
multicellular behavior that facilitates and/or prolongs survival in diverse environmental …