The aim of the present study was to compare, in chloral-hydrate anaesthetized rats, the α2-
adrenergic properties of the selective 5-HT1A receptor agonist, alnespirone (S-20499), with …

Spiroxatrine has been reported to be a 5‐HT1A serotonin receptor antagonist. Therefore
[3H] spiroxatrine was synthesized and its 5‐HT1A receptor binding properties in …

A series of new analogues of 3-[3-(4-arylpiperazinyl)-propyl]-cyclohexane-1', 5-
spirohydantoin (2), with aromatic ring fused in amide moiety (4–9) were synthesized and …

In addition to the sesquiterpene-phenol aureols (1), 6 '-chloroaureol (2), and aureol acetate
(3), eight indole alkaloids including the new N-3 '-ethylaplysinopsin (9) have been isolated …

A series of benzo [h][1, 6] naphthyridine and azepino [3, 2-c] quinoline derivatives were
prepared and evaluated to determine the necessary requirements for high affinity on the 5 …

Several-methyleneindoline bases have been reported isolated and characterizedfrom
Catharanthus, as well as from other species of plants. None of the monomeric …

Previous studies have shown that the 5-HT 1A receptor ligand, lesopitron (E-4424, 2-[4-[4-(4-
chloro-1-pyrazolyl) butyl]-1-piperazinyl] pyrimidine), exerts potent anxiolytic-like effects in …

This paper describes the 5-hydroxytryptamine3 (5-HT3) receptor antagonism of Y-25130 ((±)-
N-(1-azabicyclo [2.2. 2] oct-3-yl)-6-chloro-4-methyl-3-oxo-3, 4-dihydro-2H-1, 4-benzoxazine …

A series of N-[2-[(substituted chroman-8-yl) oxy] ethyl]-4-(4-methoxyphenyl) butylamines was
prepared and examined for their 5-HT1A receptor antagonist activity. The parent compound …

In orderto explore the structural requirements for high 5-HTia affinity, a series of
arylsubstituted IW-phenylpiperazines were synthesized and evaluated for their ability to …