Design and assessment of anti-biofilm peptides: steps toward clinical application
M Dostert, CR Belanger, REW Hancock - Journal of innate immunity, 2019 - karger.com
Highly antibiotic resistant, microbial communities, referred to as biofilms, cause various life-
threatening infections in humans. At least two-thirds of all clinical infections are biofilm …
threatening infections in humans. At least two-thirds of all clinical infections are biofilm …
Anti-biofilm peptides as a new weapon in antimicrobial warfare
D Pletzer, SR Coleman, REW Hancock - Current opinion in microbiology, 2016 - Elsevier
Highlights•To date no antibiotics have been specifically developed for biofilm infections.•Anti-
biofilm peptides directly address chronic multi-resistant bacterial infections.•They …
biofilm peptides directly address chronic multi-resistant bacterial infections.•They …
[HTML][HTML] Critical assessment of methods to quantify biofilm growth and evaluate antibiofilm activity of host defence peptides
Biofilms are multicellular communities of bacteria that can adhere to virtually any surface.
Bacterial biofilms are clinically relevant, as they are responsible for up to two-thirds of …
Bacterial biofilms are clinically relevant, as they are responsible for up to two-thirds of …
Antibiofilm peptides: potential as broad-spectrum agents
D Pletzer, REW Hancock - Journal of bacteriology, 2016 - Am Soc Microbiol
The treatment of bacterial diseases is facing twin threats, with increasing bacterial antibiotic
resistance and relatively few novel compounds or strategies under development or entering …
resistance and relatively few novel compounds or strategies under development or entering …
[HTML][HTML] Antibiofilm peptides: overcoming biofilm-related treatment failure
Health leaders and scientists worldwide consider antibiotic resistance among the world's
most dangerous pathogens as one of the biggest threats to global health. Antibiotic …
most dangerous pathogens as one of the biggest threats to global health. Antibiotic …
[HTML][HTML] Synthetic antibiofilm peptides
C De La Fuente-Núñez, MH Cardoso… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Bacteria predominantly exist as multicellular aggregates known as biofilms that are
associated with at least two thirds of all infections and exhibit increased adaptive resistance …
associated with at least two thirds of all infections and exhibit increased adaptive resistance …
[HTML][HTML] Antimicrobial and antibiofilm peptides
A Di Somma, A Moretta, C Canè, A Cirillo, A Duilio - Biomolecules, 2020 - mdpi.com
The increasing onset of multidrug-resistant bacteria has propelled microbiology research
towards antimicrobial peptides as new possible antibiotics from natural sources …
towards antimicrobial peptides as new possible antibiotics from natural sources …
[HTML][HTML] Broad-spectrum anti-biofilm peptide that targets a cellular stress response
C De la Fuente-Núñez, F Reffuveille, EF Haney… - PLoS …, 2014 - journals.plos.org
Bacteria form multicellular communities known as biofilms that cause two thirds of all
infections and demonstrate a 10 to 1000 fold increase in adaptive resistance to conventional …
infections and demonstrate a 10 to 1000 fold increase in adaptive resistance to conventional …
Antibiofilm peptides: relevant preclinical animal infection models and translational potential
GGOS Silveira, MDT Torres, CFA Ribeiro… - ACS Pharmacology & …, 2021 - ACS Publications
Biofilm-forming bacteria may be 10–1000 times more resistant to antibiotics than planktonic
bacteria and represent about 75% of bacterial infections in humans. Antibiofilm treatments …
bacteria and represent about 75% of bacterial infections in humans. Antibiofilm treatments …
[HTML][HTML] Antibiofilm peptides and peptidomimetics with focus on surface immobilization
A Andrea, N Molchanova, H Jenssen - Biomolecules, 2018 - mdpi.com
Bacterial biofilms pose a major threat to public health, as they are associated with at least
two thirds of all infections. They are highly resilient and render conventional antibiotics …
two thirds of all infections. They are highly resilient and render conventional antibiotics …