Biofilm-related infections account for at least 65% of all human infections, but there are no
available antimicrobials that specifically target biofilms. Their elimination by available …

A majority of microbial infections are associated with biofilms. Targeting biofilms is
considered an effective strategy to limit microbial virulence while minimizing the …

The problem of drug resistance is very worrying and ever increasing. Resistance is due not
only to the reckless use of antibiotics but also to the fact that pathogens are able to adapt to …

Biofilm-associated infections are difficult to manage or treat as biofilms or biofilm-embedded
bacteria are difficult to eradicate. Antimicrobial peptides have gained increasing attention as …

The recent observation that certain cationic peptides possess potent antibiofilm activity
demonstrated that small peptides could be used to treat biofilm-associated infections. Other …

Anti-biofilm peptides are a subset of antimicrobial peptides and represent promising broad-
spectrum agents for the treatment of bacterial biofilms, though some display host toxicity in …

The great clinical significance of biofilm-associated infections and their inherent
recalcitrance to antibiotic treatment urgently demand the development of novel antibiofilm …

Antimicrobial peptides (AMPs) are increasingly being considered as novel agents against
biofilms. The development of AMP-based anti-biofilm strategies strongly relies on the design …

In many infections, bacteria form surface-associated communities known as biofilms that are
substantially more resistant to antibiotics than their planktonic counterparts. Based on the …

Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …