Individual and Combined Effects of Engineered Peptides and Antibiotics on Pseudomonas aeruginosa Biofilms
Pseudomonas aeruginosa is involved in a variety of difficult-to-treat infections frequently due
to biofilm formation. To identify useful antibiofilm strategies, this article evaluated efficacy of …
to biofilm formation. To identify useful antibiofilm strategies, this article evaluated efficacy of …
Prevention of ESKAPE pathogen biofilm formation by antimicrobial peptides WLBU2 and LL37
Objectives Bacterial biofilm-dependent infections (eg cystic fibrosis, surgical sites, and
medical implants) are associated with enhanced drug-resistance and are thus difficult to …
medical implants) are associated with enhanced drug-resistance and are thus difficult to …
Biofilm formation as valuable target to fight against severe chronic infections
C Pecoraro, D Carbone, D Deng… - Current medicinal …, 2022 - ingentaconnect.com
As most countries in the world are struggling to control the COVID-19 pandemic, scientists
should warn that other infective diseases are inevitable, and antibiotic resistance to bacterial …
should warn that other infective diseases are inevitable, and antibiotic resistance to bacterial …
Action of antimicrobial peptides against bacterial biofilms
Microbes are known to colonize surfaces and form biofilms. These biofilms are communities
of microbes encased in a self-produced matrix that often contains polysaccharides, DNA and …
of microbes encased in a self-produced matrix that often contains polysaccharides, DNA and …
Synergy between conventional antibiotics and anti-biofilm peptides in a murine, sub-cutaneous abscess model caused by recalcitrant ESKAPE pathogens
D Pletzer, SC Mansour, REW Hancock - PLoS pathogens, 2018 - journals.plos.org
With the antibiotic development pipeline running dry, many fear that we might soon run out
of treatment options. High-density infections are particularly difficult to treat due to their …
of treatment options. High-density infections are particularly difficult to treat due to their …
Applying insights from biofilm biology to drug development—can a new approach be developed?
Most of the research on bacterial pathogenesis has focused on acute infections, but much
less is known about the pathogenesis of infections caused by bacteria that grow as …
less is known about the pathogenesis of infections caused by bacteria that grow as …
Biofilms: Survival and defense strategy for pathogens
A Kumar, A Alam, M Rani, NZ Ehtesham… - International Journal of …, 2017 - Elsevier
Studies on biofilm related infections are gaining prominence owing to their involvement in
majority of clinical infections. Biofilm, considered as a generic mechanism for survival used …
majority of clinical infections. Biofilm, considered as a generic mechanism for survival used …
Host Defense Peptide-Mimicking Amphiphilic β-Peptide Polymer (Bu:DM) Exhibiting Anti-Biofilm, Immunomodulatory, and in Vivo Anti-Infective Activity
Therapeutic options to treat multidrug resistant bacteria, especially when present in biofilms,
are limited due to their high levels of antibiotic resistance. Here, we report the anti-biofilm …
are limited due to their high levels of antibiotic resistance. Here, we report the anti-biofilm …
Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action
Biofilm refers to the complex, sessile communities of microbes found either attached to a
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …
surface or buried firmly in an extracellular matrix as aggregates. The biofilm matrix …
[HTML][HTML] Natural anti-biofilm agents: strategies to control biofilm-forming pathogens
R Mishra, AK Panda, S De Mandal, M Shakeel… - Frontiers in …, 2020 - frontiersin.org
Pathogenic microorganisms and their chronic pathogenicity are significant concerns in
biomedical research. Biofilm-linked persistent infections are not easy to treat due to resident …
biomedical research. Biofilm-linked persistent infections are not easy to treat due to resident …