Importance of the field: Current antibiotics have classically been developed to treat
infections involving planktonic bacterial populations in acute infection settings and are …

Many bacteria live as biofilms to cope with unfavourable surroundings. Biofilms start from (i)
a planktonic stage,(ii) initial adhesion to surfaces and (iii) formation of sessile micro-colonies …

Biofilm is a community of bacteria embedded in the extracellular matrix that accounts for
80% of bacterial infections. Biofilm enables bacterial cells to provide particular conditions …

Biofilm formation significantly contributes to microbial survival in hostile environments and it
is currently considered a key virulence factor for pathogens responsible for serious chronic …

Small cationic, amphipathic peptides with critical roles in host defenses often exhibit
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …

Host defense (antimicrobial) peptides, produced by all complex organisms, typically contain
an abundance of positively charged and hydrophobic amino acid residues. A small synthetic …

Biomaterial-related infections are a persistent burden on patient health, recovery, mortality
and healthcare budgets. Self-assembled antimicrobial peptides have evolved from the area …

Medical device related infections are a significant and growing source of morbidity and
mortality. Biofilm formation is a common feature of medical device infections that is not …

Biofilm formation on surfaces via microbial colonization causes infections and has become a
major health issue globally. The biofilm lifestyle provides resistance to environmental …

Bacterial resistance is a rapidly escalating threat to public health as our arsenal of effective
antibiotics dwindles. Therefore, there is an urgent need for new antibiotics. Drug discovery …