Biofilms are inherently difficult to treat, and mechanical disruption is the mainstay of clinical
management. With scientific progress in molecular microbiology, there is an abundance of …

Novel classes of antibiotics and new strategies to prevent and treat infections are urgently
needed because the rapid rise in drug-resistant bacterial infections in recent decades has …

Today, researchers are looking at new ways to treat severe infections caused by resistance
to standard antibiotic therapy. This is quite challenging due to the complex and …

Although biofilms have been observed early in the history of microbial research, their impact
has only recently been fully recognized. Biofilm infections, which contribute to up to 80% of …

In the biofilm form, bacteria are more resistant to various antimicrobial treatments. Bacteria in
a biofilm can also survive harsh conditions and withstand the host's immune system …

Biofilm formation is a major concern in various sectors and cause severe problems to public
health, medicine, and industry. Bacterial biofilm formation is a major persistent threat, as it …

Human oral biofilms are multispecies microbial communities that exhibit high resistance to
antimicrobial agents. Dental plaque gives rise to highly prevalent and costly biofilm-related …

Increased tolerance to antimicrobial agents is thought to be an important feature of microbes
growing in biofilms. We address the question of how biofilm organization affects antibiotic …

The relentless growth of multidrug resistance and generation of recalcitrant biofilm are major
obstacles in treating wounds, particularly in austere military environments where broad …

Biofilms are complex three-dimensional structures formed at interfaces by the vast majority
of bacteria and fungi. These robust communities have an important detrimental impact on a …