Bacterial biofilms constitute a critical problem in hospitals, especially in resuscitation units or
for immunocompromised patients, since bacteria embedded in their own matrix are not only …

Uropathogenic Escherichia coli account for the largest proportion of nosocomial infections in
the United States. Nosocomial infections are a major source of increased costs and …

Biofilms represent a multicellular growth state of bacteria that are intrinsically resistant to
conventional antibiotics. It was recently shown that a synthetic immunomodulatory cationic …

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause
chronic infections. The multifactorial nature of biofilm development and drug tolerance …

Biofilms are intricate multicellular structures created by microorganisms on living (biotic) or
nonliving (abiotic) surfaces. Medically, biofilms often lead to persistent infections, increased …

Biofilm-associated infections pose a complex problem to the medical community, in that
residence within the protection of a biofilm affords pathogens greatly increased tolerances to …

Development of novel antimicrobial agents is a top priority in the fight against multidrug-
resistant (MDR) and persistent bacteria. We developed a panel of synthetic antimicrobial …

Bacterial resistance to commonly used drugs has become a global health problem, causing
increased infection cases and mortality rate. One of the main virulence determinants in many …

Biofilms are intricate bacterial assemblages that attach to diverse surfaces using an
extracellular polymeric substance that protects them from the host immune system and …

It is widely recognized that many chronic infections of the human body have a polymicrobial
etiology. These include diabetic foot ulcer infections, lung infections in cystic fibrosis …