A high oxygen atmosphere induced apoptosis in cultured neuronal cells including PC12
cells and rat embryonic cortical, hippocampal, and basal forebrain neurons associated with …

When embryonic rat hippocampal neurons were cultured in a 50% oxygen atmosphere,
neurons gradually died after 20 h in culture. This death pattern was found to be mediated by …

In various animal models of cerebral hypoxia–ischemia, it is not clear whether neuronal
apoptosis results from hypoxia alone or whether other factors mediate this process. We …

Cerebral hypoxia/ischemia was shown to induce delayed, apoptotic neuronal death
occurring through biochemical pathways potentially sharing common events with cell …

We previously reported that PC12h cells are killed by a high oxygen atmosphere. In this
study, we further characterized this oxygen-induced cell death and found apoptotic features …

Oxygen-induced cell death in embryonic neurons is a useful in vitro model of neuronal
apoptosis to study the molecular mechanisms underlying the cell death induced by oxidative …

Widespread cerebral neuronal necrosis occurred in newborn Sprague-Dawley rats
submitted to three hours of pure oxygen (100% O2) at normal atmospheric pressure …

We have attempted to elucidate the mechanism of apoptotic cell death induced by hypoxia
(very low oxygen conditions) in neuronal cells. Human neuroblastoma SK-N-MC cells under …

Apoptosis, a form of cell death (“programmed” cell death) in which the nucleus and
cytoplasm shrink and often fragment, serves to eliminate excessive or unwanted cells during …

The cell death induced by hydroxyl radicals generated by Cu-phenanthroline and
peroxynitrite generated by 3-morpholinosydnonimine hydrochloride (SIN-1) in rat primary …