Angiotensin receptor blockers (ARBs) were developed to better antagonize the effects of
chronic overactivation of angiotensin II. In clinical studies, ARBs have consistently been …

Activation of the renin-angiotensin system plays a major role in cardiovascular morbidity and
mortality. Recently, angiotensin II receptor blockers (ARBs) have been the subject of a …

The renin–angiotensin–aldosterone system is a key therapeutic target in hypertension. The
latest meta-analysis of mortality reduction with angiotensin-converting enzyme (ACE) …

Purpose Using data from the United Kingdom General Practice Research Database (GPRD)
randomized controlled trials (RCTs) were replicated to determine whether identifiable study …

OBJECTIVE To review the role of angiotensin receptor blockers (ARBs) for the prevention of
cardiovascular events in patients with essential hypertension without other compelling …

Current guidelines for the prevention of coronary heart disease emphasize the importance of
global cardiovascular risk, which requires the evaluation and treatment of multiple risk …

Introduction Antihypertensive drugs are used preventatively to lower the risk of
cardiovascular disease events. Comparative effectiveness studies on angiotensin …

Beneficial effects of angiotensin converting enzyme inhibitors (ACEI) and angiotensin type 1
receptor (AT1) blockers in patients with cardiovascular and renal diseases have been …

Methods. In order to explore the potential influence of ARBs on MI, we performed a more
comprehensive meta-analysis, including all major international, randomized trials (18 trials …

Inhibitors of the renin-angiotensin system remain a cornerstone of cardiovascular
pharmacotherapy. Although angiotensin converting enzyme inhibitors (ACEIs) have been …